نتایج جستجو برای: human breast adenocarcinoma mcf

تعداد نتایج: 1890575  

Journal: :iranian biomedical journal 0
محمد بربرستانی mohammad barbarestani ایرج راگردی کاشانی iraj ragerdi kashani فریده اعتصام farideh etesam محمدعلی شکرگزار mohammad ali shokrgozar میرعباس عبدالوهابی mir abbas abdolvahabi پیمان حداد peiman haddad محمدحسین نوری موکوهی

background: norepinephrine plays a trophic role in the control of cell replication and differentiation in target cells that express adrenergic receptors. methods: in this study, we have tested the influence of infraphysiological, physiological and supraphysiological concentrations (0.0001 nm, 1 nm, 10000 nm) of human norepinephrine on the proliferation of breast cancer cells (human breast adeno...

Farideh Etesam, Iraj Ragerdi Kashani, Mir Abbas Abdolvahabi, Mohammad Ali Shokrgozar, Mohammad Barbarestani, Mohammad Hossein Noori Mokohi, Mostafa Hosseni, Peiman Haddad,

Background: Norepinephrine plays a trophic role in the control of cell replication and differentiation in target cells that express adrenergic receptors. Methods: In this study, we have tested the influence of infraphysiological, physiological and supraphysiological concentrations (0.0001 nM, 1 nM, 10000 nM) of human norepinephrine on the proliferation of breast cancer cells (human breast adeno...

Introduction: Breast cancer is one of the most prevalent malignancies among women. Patients whose suffering from this condition, as a result of the use of conventional therapies often have a poor response to treatment and the relapse among them is frequent. In this study, the effects of staphylococcal enterotoxin type B on BAK، FAS، BAX، TNF-a، BCL-2 و Survivin genes expression in human breast ...

2015
MANDI M. HOPKINS XIAOXING FENG MENGWEI LIU LAUREN P. PARKER DAVID W. KOH

Transient receptor potential, melastatin-2 (TRPM2) is a plasma membrane cation channel with important roles in sensory functions and promoting cell death. However, we demonstrated here that TRPM2 was present in the nuclei of MCF-7 and MDA-MB-231 human breast adenocarcinoma cells, and its pharmacologic inhibition or RNAi silencing caused decreased cell proliferation. Neither an effect on prolife...

Further investigations on phytochemical constituents of dichloromethane extract fromroots of Salvia lachnocalyx (S. lachnocalyx) led to the isolation and identification of eightknown diterpenoids from this plant for the first time. The chemical structures of the purifiedcompounds were elucidated using spectroscopic analyses including EI-MS, 1H and 13C NMR andby compariso...

Journal: :Molecules 2012
Suvitha Syam Siddig Ibrahim Abdelwahab Mohammed Ali Al-Mamary Syam Mohan

Several chalcones were synthesized and their in vitro cytotoxicity against various human cell lines, including human breast adenocarcinoma cell line MCF-7, human lung adenocarcinoma cell line A549, human prostate cancer cell line PC3, human adenocarcinoma cell line HT-29 (colorectal cancer) and human normal liver cell line WRL-68 was evaluated. Most of the compounds being active cytotoxic agent...

Further investigations on phytochemical constituents of dichloromethane extract fromroots of Salvia lachnocalyx (S. lachnocalyx) led to the isolation and identification of eightknown diterpenoids from this plant for the first time. The chemical structures of the purifiedcompounds were elucidated using spectroscopic analyses including EI-MS, 1H and 13C NMR andby compariso...

Journal: :Bioorganic & medicinal chemistry letters 2012
Narender Reddy Emmadi Krishnaiah Atmakur Ganesh Kumar Chityal Sujitha Pombala Jagadeesh Babu Nanubolu

A series of fluorinated tetrahydropyrano[3,2-c]chromenes and dihydropyrano[3,2-b]pyran derivatives have been synthesized and their in vitro cytotoxic activities have been determined in cervical cancer cell line (HeLa), human breast adenocarcinoma cell line (MDA-MB-231 and MCF-7) and human alveolar adenocarcinoma cell line (A549). Compounds 4g, 4k, 4p showed a very potent activity against MDA-MB...

ژورنال: ارمغان دانش 2020

Aim: Bcl-2 is a potential target for tumor treatment. The inhibition of the Bcl-2 production is research target of attract in the field of anti-cancer drug development. Recently, the assessment of antitumor activity appeared to be promising for pyrazole derivatives. Therefore, this study was designed to investigate the anti-cancer effects of novel pyrazole derivatives (HN1and HN2.). Material an...

Journal: :Chemical communications 2008
Fei Yan Yan Zhang Hsiang-kuo Yuan Molly K Gregas Tuan Vo-Dinh

A methylene blue-encapsulated apoferritin complex shows cytotoxic effects on MCF-7 human breast adenocarcinoma cells when irradiated at the appropriate wavelength.

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