BACKGROUND/AIMS The PCK rat model of polycystic kidney disease is characterized by the progressive development of renal medullary cysts. Here, we evaluated the suitability of high resolution ultrasonography (HRU) to assess the kidney and cyst volume in PCK rats, testing three different ultrasound image analysis methods, and correlating them with kidneys weights and histological examinations. ...

BACKGROUND Pediatric hospitals frequently perform congenital heart surgery in adults with congenital heart disease. The impact of these admissions on pediatric hospital resources is unknown. Our goals were to examine resource use by adults undergoing congenital heart surgery in pediatric hospitals, explore the association between high resource use (HRU) and inpatient death, and identify HRU ris...

Greedy based approach for view selection at each step selects a beneficial view that fits within the space available for view materialization. Most of these approaches are focused around the HRU algorithm, which uses a multidimensional lattice framework to determine a good set of views to materialize. The HRU algorithm exhibits high run time complexity as the number of possible views is exponen...

Accurate predictions of sediment yield from distributed models of runoff and sediment yield depends in part of how well matched the model structure is to input data spatial representation. This study investigated how model structure and input data representation affect sediment predictions made using the Soil and Water Assessment Tool (SWAT). The study focused on the integration of two specific...

RATIONALE, AIMS AND OBJECTIVES Clinical trial data suggest that patients who have received bisphosphonates continue to benefit from them after discontinuation. However, data from real-world clinical practice are inconclusive. We assessed the impact of persistence and discontinuation on health resource utilization (HRU) and fracture rate in women who were prescribed oral bisphosphonates. METHO...

OBJECTIVE To understand the impact of anemia on health-related quality of life (HRQOL) and healthcare resource utilization (HRU) in patients with HIV/AIDS. METHODS In 2003, adults with HIV/AIDS were recruited through 114 US STD/HIV clinics to complete self-administered questionnaires. Adults reporting anemia as a side-effect of antiretroviral therapy (ART) during the past month were considere...

BACKGROUND Persons with concomitant heart failure (HF) and diabetes mellitus constitute a growing population whose quality of life is encumbered with worse clinical outcomes as well as high health resource use (HRU) and costs. METHODS AND RESULTS Extensive data on HRU and costs were collected as part of a prospective cost-effectiveness analysis of a self-care intervention to improve outcomes ...

Water movement and storage within an agricultural watershed can be simulated at different spatial resolutions of land areas or hydrological response units (HRUs). Interactions between HRUs in space and time vary with the HRU sizes, such that natural scaling relationships are confounded with the simulation scales. Scaling concepts can be tested using the AgroEcoSystemWatershed (AgES-W) model wit...

OBJECTIVE To explore the relationship between the severity of urinary urge incontinence (UUI) on healthcare resources utilization (HRU) and loss of labor productivity of subjects with overactive bladder (OAB) in the general population in Spain. METHODS Secondary analysis of a cross-sectional web-based study conducted in the general population >18 years, through a battery of HRU questions aske...

BACKGROUND Fibromyalgia (FM) is a chronic disorder characterized by widespread, persistent pain. Prospective and retrospective studies have demonstrated substantial health-care costs associated with FM in a number of countries. This study evaluated and compared health-resource use (HRU) and associated costs related to FM in routine clinical practice across the US, France, and Germany. METHODS...