background: sickle cell disease is a genetic disorder of hemoglobin causing myriad of pathology including anemia. the purpose of this study was to evaluate the baseline values of steady state hemoglobin and packed cell volume as a guide to managing the early recognition of hemolytic crises in sickle cell anemia. methods: a cross-sectional study was conducted among the sickle cell patients atten...

Sickle cell disease is an autosomal recessive hematological disorder resulting from a missense point mutation in the beta chain of haemoglobin molecule. This article reports case homozygous sickle adult patient with long-standing history non-healing ulcer

The prevalence of nocturnal enuresis (wet at least two nights a week) was investigated in children, aged 8, who were being followed up as part of a prospective cohort study. There were 175 children with homozygous sickle cell disease, 106 with sickle cell haemoglobin C disease, and 150 controls with a normal haemoglobin genotype. In homozygous sickle cell disease, 48 boys (52%) and 31 girls (38...

Background: Sickle cell anemia is relatively common in Khuzestan province located in Southwest Iran. The characteristics of sickle cell disease in Iran are apparently different from other regions some of these characteristics might be related to β-chain haplotypes. The purpose of this study was to determine the frequency of β-chain haplotypes in 50 patients with homozygous sickle cell anemia in...

OBJECTIVES This study compared the subjective well-being of adults with homozygous sickle cell (SS) disease to a matched group of healthy adult peers. The differential influence of sociodemographic factors on the subjective well-being of Sickle Cell patients was also examined. METHODS The Ferran and Powers Quality of Life Index and the Positive and Negative Affect Schedule were used to assess...

Abstract Background Prevalence of hereditary blood diseases such as sickle cell anemia, sickle thalassemia and thalassemia major are high in Khuzestan province. Sickle cell anemia and beta-thalassemia are predominantly common in Iranian Arabs. Pulmonary complications account for a large proportion of morbidity and mortality in patients with and sickle cell disease. Periodic lung function asse...

conclusions ultimately, we can conclude that the hemoglobin level at the time of admission and before delivery, the type of disease, gestational age, and transfusion could be effective factors of patient mortality. results the mean maternal age was 27.60 ± 6.37 years. the hemoglobin level at hospital admission was 8.9 ± 1.61 g/dl for the survivors and 7.73 ± 1.19 g/dl for the deceased patients ...