AIM To investigate the ability of human amniotic fluid stem cells and human dental pulp stem cells to differentiate into insulin-producing cells. METHODS Human amniotic fluid stem cells and human dental pulp stem cells were induced to differentiate into pancreatic β-cells by a multistep protocol. Islet-like structures were assessed in differentiated human amniotic fluid stem cells and human d...

homeobox (hox) genes are contributed in the genetic control of development of the body plan, pattern formation, and cell fate determination and the other several key developmental processes. hox genes are also known as selector genes because expression within a given section of the embryo will cause its cells to choose a particular developmental path. hox genes encode transcription factors that...

PURPOSE To screen the visual system homebox 1 (VSX1) gene in Saudi Arabian keratoconus patients. METHODS We sequenced the entire coding region, exon-intron boundaries in clinically confirmed keratoconus patients (n=55) and 50 ethnically matched healthy controls. All cases and controls were unrelated. RESULTS Sequencing VSX1 revealed the presence of five nucleotide changes, 3 of which were n...

Many bio-signals of the chronic patients could be measured by various bio-devices and transferred to back-end system over the wireless network through the homebox. In a home-care environment, it becomes more complex to reliably process transmitting and receiving these bio-signals by the homebox. While the bio-devices increasing, the process is even much more complex. In addition, the chronic pa...

The chicken homebox containing gene, CdxA (formerly CHox-cad), was previously shown to be expressed during gastrulation. Localization of CdxA transcripts by in situ hybridization to tissue sections revealed that, during gastrulation, expression of this gene exhibits a posterior localization along the primitive streak. The transcripts are localized to epiblast cells in the vicinity of the primit...

One of the distinguishing features of vertebrate development is the elaboration of the anterior neural plate into forebrain and midbrain, yet little is known about the early tissue interactions that regulate pattern formation in this region or the genes that mediate these interactions. As an initial step toward analyzing the process of regionalization in the anterior-most region of the brain, w...

The segment-polarity class of segmentation genes in Drosophila are primarily involved in the specification of sub-segmental units. In addition, some of the segment-polarity genes have been shown to specify cell fates within the central nervous system. One of these loci, gooseberry, consists of two divergently transcribed genes, gooseberry and gooseberry neuro, which share a paired box as well a...