diabetes mellitus is the most common cause of chronic renal disorders and end-stage kidney disease in developed countries. it is the major cause of dialysis and transplantation. failure in renal function causes wide disorders in the body. diabetes results in wide range of alterations in the renal tissue. it is believed that early histological changes in diabetic nephropathy are detectable 2 yea...

In a recent publication we described a microscopical technique called Ultramicroscopy, combined with a histological procedure that makes biological samples transparent. With this combination we can gather three-dimensional image data of large biological samples. Here we present the theoretical analysis of the z-resolution. By analyzing the cross-section of the illuminating sheet of light we der...

  Diabetes mellitus is the most common cause of chronic renal disorders and end-stage kidney disease in developed countries. It is the major cause of dialysis and transplantation. Failure in renal function causes wide disorders in the body. Diabetes results in wide range of alterations in the renal tissue. It is believed that early histological changes in diabetic nephropathy are detectabl...