SUMMARY : Yellow-brown bodies were observed in the sinusoids of lymph nodes and histiocytes. The authors confirmed immunohistochemical reactivity of alpha-1-antichymotrypsin, lysozyme, and alkaline phosphatase in non-phagocytic histiocytes, and phagocytic histiocytes which contained yellow-brown bodies. Histio-cytes with yellow-brown bodies were not reacted to alpha-1-antichymotrypsin, lysozyme...

AIMS To determine whether myelodysplastic syndromes (MDS) are associated with sea blue histiocytosis in the bone marrow. METHODS A retrospective review of bone marrow aspirates from 35 patients presenting consecutively with MDS and from 20 patients with each of the following: normal marrow appearance (routine staging for non-Hodgkin's lymphoma), polycythaemia rubra vera, immune thrombocytopen...

background: langerhans' cell histiocytosis (lch) is a reactive proliferative disease of unknown pathogenesis characterized by proliferation of langerhans cells. involvement of bone marrow (bm), liver and lung are related to high risk factors and poor survival. the aim of this report is to highlight the clinical and haematological findings of 5 cases of lch with bm infiltration which may help to...

Immunization of mice or guinea pigs with BCG rendered all or most of the histiocytes of these animals resistant to necrotization by virulent H37Rv; this cellular resistance was mediated by immune serum. Immune mouse histiocytes (from BCG-immunized animals) were able to induce cellular resistance in normal homologous and heterologous (rabbit) animal species; mouse histiocytic ribosomes were also...