background: advantages of herbal drugs have been known to human being for many years and they have been used for treatment of many diseases. nowadays, inflammation is known to be one of the basic pathologic causes of the diseases. objective: in this study the anti-inflammatory effect of thymus kotschyanus boiss & hohen was investigated. methods: forty two wistar rats were used in three divided ...

This investigation was performed in order to assess the inflammatory response induced by Naja haje arabica venom (NhaV) in rat hind paw. The inflammatory response was estimated by measuring the edema with a Plethysmometer. The venom (0.625-10μg/paw) produced a dose and timedependent increase in non-hemorrhagic paw edema. The response to NhaV was maximal within 15 min and disappeared in 24 h. Fi...

Anti-inflammatory potency of 5-hydroxypyrimidine derivatives SNK-411 (2-isobutyl-4,6-dimethyl-5-hydroxypirimidine) and SNK-578 (hydrochloride 2-isobutyl-4,6-dimethyl-5-hydroxypirimidine) was evaluated on the model complete Freund`s adjuvant (CFA)-induced exudative inflammation in experiment 60 outbreed male rats weighing 180–200 g comparison with prednisolone. Prednisolone, were injected twice:...

There are some evidences regarding anti-allergic and anti-inflammatory effects of Licorice common in traditional medicine and its usefulness in Diabetes mellitus and Diabetes insipidus and its stimulatory effect on admeocortical gland. This medicinal plant contains glycyrrhizin, sterogenic substances, cumarins, flavonoids, sterols, choline, asparagine and glaberin. Glycyrrhizin and glaberin hav...

Anti inflammatory potential of aerial parts of Phyllanthus longiflorus was investigated in the present study using acute and chronic inflammatory models. Carrageenan, dextran and formalin were used as an edematogenic agent to induce hind paw edema in rats and the mean increase in paw volume were measured using plethysmometer. Results showed that methanol extract of Phyllanthus longiflorus at th...

The significant inhibitory action of diclofenac formulated in mixed micelles of lecithin with cholate or deoxycholate was observed on the rat hind paw edema induced by carrageenan. In the primary stage, mixed micelle formulation of deoxycholate was more effective compared with that of cholate. However, in the final term, the inhibitory action was similar in both formulations. In a previous stud...

Carrageenan produces both inflammation and pain when injected in mouse paws via enhancement of reactive oxygen species formation. We have investigated an effect of astaxanthin extracted from Litopenaeus vannamei in carrageenan-induced mice paw edema and pain. The current study demonstrates interesting effects from astaxanthin treatment in mice: an inhibition of paw edema induced in hind paw, an...

BACKGROUND Cannabinoid receptor agonists inhibit inflammatory hyperalgesia in animal models. Nonselective cannabinoid receptor agonists also produce central nervous system (CNS) side effects. Agonists selective for CB2 cannabinoid receptors, which are not found in the CNS, do not produce the CNS effects typical of nonselective cannabinoid receptor agonists but do inhibit acute nociception. The ...

In this study the anti-inflammatory activity of ethanolic extract of Cynanchum acutum was evaluated. Cynanchum acutum has a large history of herbal use because of pharmaceutical characteristics and the medicinal values of the Cynanchum acutum have been mentioned in ancient literature as useful in disorders. The effects of ethanolic extracts of Cynanchum acutum were studied on carrageen an induc...