the aim of this study was to formulate and evaluate microencapsulated controlled release preparations of a highly water/soluble drug, salbutamol sulphate by (water in oil) in oil emulsion technique using ethyl cellulose as the retardant material. various processing and formulation parameters such as drug/polymer ratio, stirring speed, volume of processing medium were optimized to maximize the e...

Background and Objective: Higuchi’s method of determining fractal dimension (HFD) occupies a valuable place in the study wide variety physical signals. In comparison to other methods, it provides more rapid, accurate estimations for entire range possible dimensions. However, major difficulty using is correct choice tuning parameter (kmax) compute most results. past researchers have used various...

There exist several methods for calculating the fractal dimension of objects represented as 2D digital images. For example, Box counting, Minkowski dilation or Fourier analysis can be employed. However, there appear to be some limitations. It is not possible to calculate only the fractal dimension of an irregular region of interest in an image or to perform the calculations in a particular dire...

K. Premaratne, E. I. Jury, and M. Mansour, “An algorithm for model reduction of 2-D discrete time systems,” IEEE Trans. Circuits Syst. , vol. 37, pp. 1116-1132, Sept. 1990. M. Kawamata, T. Lin, and T. Higuchi, “Minimization of sensitivity of 2-D state-space digital filters and its realization to 2-D balanced realizations,” in Proc. IEEE I987 Int. Symp. Circuits and Syst. vol. 2, pp. 710-713, Ph...

Chondroitin sulfate and sodium alginate were incorporated in different ratios to prepare glutaraldehyde (GA) crosslinked microspheres by water-in-oil emulsion crosslinking method for delivery of 5-flurouracil (5-FU) to colon. Chemical interaction, surface morphology, thermal degradability, crystallinity evaluation, elemental analysis and drug release results were computed by using FTIR, SEM, DS...