background and objective: dyslipidemia has become a common problem in human immunodeficiency virus (hiv) disease, especially in patients on combination antiretroviral therapy. in this study we aimed to determine the prevalence of dyslipidemia and metabolic abnormalities in 2 groups of hiv infected patients receiving highly active antiretroviral therapy (haart) and antiretroviral-naive patients....

case presentation a 52-year-old malay gentleman, with hepatitis c virus and hiv infection was admitted to the intensive care unit for severe lactic acidosis, with concurrent escherichia coli bacteremia with multiorgan dysfunction. the patient was started on highly active antiretroviral therapy, which included tenofovir, 5 weeks before presentation. antimicrobial therapy, continuous veno-venous ...

pulmonary hypertension is rare but is one of the complications that occur due to hiv infection. symptoms of hiv-associated pulmonary arterial hypertension are often non-specific but the main symptom of the disease is dyspnea. in this cross-sectional study, we measured systolic pulmonary arterial pressure (spap) by echocardiographic methods among hiv-positive patients who received art. this rese...

The number of people on highly active antiretroviral therapy (HAART) in South Africa has risen from < 2000 in October 2003, to almost 200,000 by the end of 2005. Yet South Africa's performance in terms of HAART coverage is poor both in comparison with other countries and the targets set by the government's own Operational Plan. The public-sector HAART "rollout" has been uneven across South Afri...

The dynamics of HIV replication and the high frequency of point mutations have proven to be the Achilles heel of HAART. These random mutations are the basis of therapy failure, regardless of the factors initially leading to failure – non-adherence, poor absorption, inadequate potency of the regimen and so forth. The technology to monitor and identify resistance has become available for clinicia...

Lipoatrophy (LA) is a common and now well-recognized complication of highly active antiretroviral therapy (HAART). Over the last decade as knowledge of the mechanisms behind LA has developed, several antiretroviral drugs, in particular, have emerged as the likely agents responsible for this complication. This has been supported by studies comparing alternative HAART regimens and by those in whi...

Background and Objective: Dyslipidemia has become a common problem in human immunodeficiency virus (HIV) disease, especially in patients on combination antiretroviral therapy. In this study we aimed to determine the prevalence of dyslipidemia and metabolic abnormalities in 2 groups of HIV infected patients receiving highly activ...