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background: human pathogens that can cause infertility may also affect sperm count and quality. viral infections can be considered as direct and/or indirect cause of male factor infertility. objective: our goal was to investigate the prevalence of herpes simplex virus in the semen of infertile men attending the avicenna infertility clinic, and to compare it with the herpes virus serology result...

objective herpes simplex virus (hsv), one of the most common sexually transmitted disease is a worldwide .this study aimed to prevalence of herpes simplex virus of pregnancy in iran. methods: we searched pubmed, scopus, ovid, science direct and national databases were searched: magiran, iranmedex and science information database (sid) up to october 2015.eventually, we included five studies that...

background and aims: several drugs are being used in treatment of hsv infection in human but still introducing an effective safe drug is desirable. methods: we investigated the inhibitory effect of morphine on replication of hsv in vitro. results: the results indicated that a concentration of up to 200 ug/ml morphine had a limited effect on vero cell viability. at this concentration the growth ...

Introduction: Herpes Simplex Virus type 2 (HSV-2)  is a highly prevalent sexually transmitted infection (STI) The prevalence of HSV-2 infection is increasing in many populations and geographic areas . Herpes simplex virus type 2 (HSV-2) is the cause of most genital herpes and is almost always sexually transmitted. Most HSV-2 infections are consequently expected to occur after the onset of sexua...

The replication of herpes simplex virus type I and herpes simplex virus type 2 was studied in two isolated hamster cell lines. These lines developed after being treated with herpes simplex virus type 2 inactivated with 7,~2-dimethylbenz(a)anthracene. One cell line that developed, HDC-22, had a hypodiploid chromosome number and was missing a D-group chromosome. Growth studies revealed that this ...

Brown alga, Turbinaria conoides was successively extracted with n-hexane, cyclohexane, methanol and ethanol:water (1:1). The extracts were evaluated for antibacterial and antifungal activities by disc diffusion method. Minimal inhibitory concentration was determined for active extracts by broth dilution method. The antiviral activity and cytotoxicity of the extracts were tested in human embryon...

    Acyclovir (9-[2-hydroxyethoxymethyl] guanine) is an acyclic nucleoside analogue of guanosine which is a potent and selective antiviral agent. Acycloviris converted to the monophosphate by thymidine kinase the virus-specific form of this enzyme and is subsequently converted to the triphosphate by the host cell kinase. Acyclovir triphosphate inhibits viral DNA-polymerase terminating the chain...