9. REFERENCES ACGIH. 1986. Documentation of the threshold limit valves and biological exposure indices. 5th ed. Cincinnati, OH: American Conference of Governmental Industrial Hygienists, 296. ACGIH. 2004. Threshold limit values for chemical substances and physical agents and biological exposure indices. Cincinnati, OH: American Conference of Governmental Industrial Hygienists. Adeshina F, Todd ...

White rot fungi of the genus Phlebia have demonstrated a high capacity to degrade organic pollutants, including polychlorinated dibenzo-p-dioxins and polychlorinated biphenyls. In this study, we evaluated the ability of 18 white rot fungi species of genus Phlebia to degrade heptachlor and heptachlor epoxide, and described the metabolic pathways by selected white rot fungi. Phlebia tremellosa, P...

Heptachlor is a polychlorinated cyclodiene insecticide that was extensively used prior to 1970 to kill termites, ants, and soil insects in seed grains and on crops. In 1983, the manufacturers voluntarily cancelled its registered uses, with the exception of termite and fire ant control. Currently, the only permitted use of heptachlor is for fire ant control in buried power transformers; however,...

Heptachlor is a persistent cyclodiene pesticide that affects GABAergic function. Recent reports indicate that heptachlor exposure also alters dopamine transporter (DAT) expression and function in adult mice. The aim of this study was to determine whether gestational, perinatal, and/or adolescent heptachlor exposure in rats altered dopamine-receptor and DAT binding. Adolescent exposure to dieldr...

Changes in biochemical status of nerve terminals in the corpus striatum, one of the primary brain regions affected in Parkinson's disease, were studied in groups of C57BL/6 mice treated by ip injection three times over a 2-week period with 3--100 mg/kg heptachlor. On average, the maximal rate of striatal dopamine uptake increased > 2-fold in mice treated at doses of 6 mg/kg heptachlor and 1.7-f...

On the basis of degradation properties of Phanerochaete chroysosporium ME 446 found in white-rot fungi in respect of many organic compounds with toxic, mutagenic and carcinogenic characteristics, the physiological conditions effective for the degradation of heptachlor (1, 4, 5, 6, 7, 8, 8heptachloro-3a, 4, 7, 7a-tetrahydro-4, 7-methanoindene), an organic chlorine used in insecticides Phanerocha...

The insecticides chlordane and heptachlor in human body fat and plasma have been linked to many types of cancers (brain, breast, leukemia, lymphoma, prostate, and testicular). The US Environmental Protection Agency (US EPA) calculated that 30 million homes were treated with chlordane from 1950 until it was banned in 1987, and that occupants of these chlordane-treated homes have exposures up to ...

Although banned in the 1970s, significant levels of the organochlorine pesticide heptachlor are still present in the environment raising concern over potential human exposure. In particular, organochlorine pesticides have been linked to an increased risk of Parkinson's disease. Studies from our laboratory and others have demonstrated that exposure of laboratory animals to heptachlor alters the ...