نتایج جستجو برای: hepatovirus

تعداد نتایج: 39  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2015
Jan Felix Drexler Victor M Corman Alexander N Lukashev Judith M A van den Brand Anatoly P Gmyl Sebastian Brünink Andrea Rasche Nicole Seggewiβ Hui Feng Lonneke M Leijten Peter Vallo Thijs Kuiken Andreas Dotzauer Rainer G Ulrich Stanley M Lemon Christian Drosten

Hepatitis A virus (HAV) is an ancient and ubiquitous human pathogen recovered previously only from primates. The sole species of the genus Hepatovirus, existing in both enveloped and nonenveloped forms, and with a capsid structure intermediate between that of insect viruses and mammalian picornaviruses, HAV is enigmatic in its origins. We conducted a targeted search for hepatoviruses in 15,987 ...

2017
Anshuman Das Asuka Hirai-Yuki Olga González-López Bethany Rhein Sven Moller-Tank Rachel Brouillette Lucinda Hensley Ichiro Misumi William Lovell John M. Cullen Jason K. Whitmire Wendy Maury Stanley M. Lemon

Receptor molecules play key roles in the cellular entry of picornaviruses, and TIM1 (HAVCR1) is widely accepted to be the receptor for hepatitis A virus (HAV), an unusual, hepatotropic human picornavirus. However, its identification as the hepatovirus receptor predated the discovery that hepatoviruses undergo nonlytic release from infected cells as membrane-cloaked, quasi-enveloped HAV (eHAV) v...

Journal: :Scientific reports 2016
Jie-mei Yu Li-li Li Cui-yuan Zhang Shan Lu Yuan-yun Ao Han-chun Gao Zhi-ping Xie Guang-cheng Xie Xiao-man Sun Li-li Pang Jian-guo Xu W Ian Lipkin Zhao-Jun Duan

Hepatitis A virus (HAV) is a hepatotropic picornavirus that causes acute liver disease worldwide. Here, we report on the identification of a novel hepatovirus tentatively named Marmota Himalayana hepatovirus (MHHAV) in wild woodchucks (Marmota Himalayana) in China. The genomic and molecular characterization of MHHAV indicated that it is most closely related genetically to HAV. MHHAV has wide ti...

Journal: :Voprosy virusologii 2022

Within the last decade, a large number of viruses genetically related to human hepatitis have been identified in different animal species, including monkeys. Numerous A virus (HAV, Picornaviridae: Hepatovirus: Hepatovirus A) were detected various mammalian species 20152018, predominantly bats and rodents, but also shrews, seals marsupials. Zoonotic E (HEV, Hepeviridae: Orthohepevirus: Orthohepe...

2012
Zahid Hussain

Hepatitis A virus (HAV) is a member of the Hepatovirus genus of Picornaviridae family. HAV is a non-enveloped (naked), linear, single stranded RNA virus of an icosahedral symmetry measuring 27-32 nm in diameter (Feinstone, 1973). The infectious particle consists of capsid protein and RNA genome (Fig. 1). The buoyant density of the mature particle is 1.33g/cm3 in CsCl solutions and the sedimenta...

2017
Osvalda De Giglio Giuseppina Caggiano Francesco Bagordo Giovanna Barbuti Silvia Brigida Federica Lugoli Tiziana Grassi Giuseppina La Rosa Luca Lucentini Vito Felice Uricchio Antonella De Donno Maria Teresa Montagna

According to Italian Ministerial Decree No. 185 of 12 June 2003, water is considered suitable for irrigation if levels of fecal bacteria (i.e., Escherichia coli and Salmonella) are within certain parameters. The detection of other microorganisms is not required. The aim of this study is to determine the bacteriological quality of groundwater used for irrigation and the occurrence of enteric vir...

Journal: :Journal of virology 2008
Mehran Bakhshesh Elisabetta Groppelli Margaret M Willcocks Elizabeth Royall Graham J Belsham Lisa O Roberts

Avian encephalomyelitis virus (AEV) is a picornavirus that causes disease in poultry worldwide, and flocks must be vaccinated for protection. AEV is currently classified within the hepatovirus genus, since its proteins are most closely related to those of hepatitis A virus (HAV). We now provide evidence that the 494-nucleotide-long 5' untranslated region of the AEV genome contains an internal r...

2005
P. VASICKOVA L. DVORSKA

Viruses cause many diseases in plants, animals, and humans. They are strict intracellular parasites with cellular specificity. Viral particles can be transmitted by different routes, such as contaminated food and water. People usually get infected orally, after ingestion of products contaminated during processing or subsequent handling or preparation. This review article is focused on the most ...

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