objective(s):lead (pb) is a toxic metal inducing many destructive effects leading to a broad range of physiological, biochemical, and neurological dysfunctions in humans and laboratory animals. materials and methods: here, we investigated the effect of chronic exposure to pb (50 mg/l) on oxidative stress, hepatotoxicity, nephrotoxicity, and lipid profile of two different age groups of female ra...

The paper reviews some of the mechanisms implicated in hepatotoxicity, which is induced by an excess lipids. spans a wide variety topics: from molecular lipids, to therapy hyperlipidemia, hepatotoxicity lipid-lowering drugs. NAFLD currently leading cause chronic liver disease Western countries; are only partially understood and there no effective therapeutic interventions. prevalence constantly...

Background: Hyperlipidemia is considered a modifiable risk factor for cardiovascular disease and atherosclerosis. Drugs of first choice, Statins, despite being well tolerable, are accompanied by many adverse effects. To tackle the shortcomings standard drugs, there dire demand to make an agent which equates better response. This study evaluated anti-hyperlipidemic comparative effects Zinc compl...

Hyperlipidemia, manifested as hypercholesterolemia and/or hypertriglyceridemia, is a condition characterized by decrease in HDL levels with an increase one or more of plasma lipids, including triglycerides cholesterol, cholesterol esters, phospholipids, lipoproteins VLDL and LDL. It also major problem leading to obesity, stroke, myocardial infarction, atherosclerosis, type 2 diabetes, degenerat...

Introduction: Paraquat is a bipyridil herbicide commonly used in modern agriculture for weed and pest control. poisoning usually occurs through direct ingestion suicidal intent, causing mortality as consequence to oxidative damage, inflammation multi-organ failure.
 Objectives: In this study, we investigated the ameliorative potential of Cucurbita pepo fruit on paraqaut-induced inflammatio...

Objective(s):Lead (Pb) is a toxic metal inducing many destructive effects leading to a broad range of physiological, biochemical, and neurological dysfunctions in humans and laboratory animals. Materials and Methods: Here, we investigated the effect of chronic exposure to Pb (50 mg/l) on oxidative stress, hepatotoxicity, nephrotoxicity, and lipid profile of two different age groups of female r...

background: although lipid lowering agents as statins are used frequently in hyperlipidemic patients as well as patients with cardiac disease, they could have major hepatic side effects, the aim of this study is to evaluate the safety of statins mainly atorvastatin on liver as estimated by liver aminotransferase assay. m aterials and methods: patients with indication of atorvastatin were includ...

With the aim of improving their physical performance, athletes and non-athletes have been using anabolicandrogenic steroids (AAS). Over the past several decades, there has been an increase in the prevalence of AAS use without adequate supervision or monitoring. We present three cases of AAS-related liver injury with the intention to discuss the use of nutritional supplements as a growing public...

We report a patient with end-stage renal disease status after two renal transplantations. Milky-like ascites was noted since the immunosuppressant agent was switched to sirolimus (1 mg/day). Chylous ascites was diagnosed owing to the triglyceride of dialysate to serum being 15.98:15.99. Series studies were all negative. It is highly suspected that the cause of chylous ascites is sirolimus relat...

We report a patient with end-stage renal disease status after two renal transplantations. Milky-like ascites was noted since the immunosuppressant agent was switched to sirolimus (1 mg/day). Chylous ascites was diagnosed owing to the triglyceride of dialysate to serum being 15.98:15.99. Series studies were all negative. It is highly suspected that the cause of chylous ascites is sirolimus relat...