نتایج جستجو برای: hepatotoxic effect
تعداد نتایج: 1642793 فیلتر نتایج به سال:
background: mentha longifolia is one of the aromatic medicinal plant belongs to lamiaceae family. there are some active ingredients in the essential oil of m. longifolia, which potentially could impair the hepatic function. the aim of this study was to find the maximum dose of essential oil of m. longifolia (eoml) that does not show any hepatic deterioration. methods: adult wistar rats fed diff...
INTRODUCTION Numerous studies have confirmed that zebrafish and mammalian toxicity profiles are strikingly similar and the transparency of larval zebrafish permits direct in vivo assessment of drug toxicity including hepatotoxicity in zebrafish. METHODS Hepatotoxicity of 6 known mammalian hepatotoxic drugs (acetaminophen [APAP], aspirin, tetracycline HCl, sodium valproate, cyclophosphamide an...
The present study seeks to evaluate the alcoholic extract of aerial part of H.Sanguinea for its anti-hepatotoxic effect against carbon tetrachloride (CCl4)
Blood samples of animals from groups I and II were taken for liver function tests by cardiac puncture under ether anaesthesia Hepatotoxicity due to antitubercular drugs is found to be mediated through oxidative stress and free radical damage to hepatocytes (1, 2, 3). The antioxidants α-tocopherol and selenium are known exert beneficial effect in antitubercular drugs induced hepatotoxicity (4, 5...
This preliminary study was undertaken to investigate some biochemical and histological effects of consumption of Talinum triangulare (L.) Juss – supplemented diet in hepatotoxic rats in which liver damage was induced with paracetamol. Thirty female rats were divided into six groups of five rats per group for control, hepatotoxic and non-hepatotoxic groups and were fed 5% or 10% T. triangulare-s...
A 33 year old woman developed a florid form of chronic active hepatitis after exposure to halothane. Histological and immunological data suggested that autoimmune type chronic active hepatitis antedated the acute hepatotoxic sequelae of the hatothane anaesthesia. Studies on the immuno regulatory functions of peripheral blood lymphocytes revealed a marked defect in suppressor cell function. It i...
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