نتایج جستجو برای: hepatotoxic effect

تعداد نتایج: 1642793  

Journal: :iranian journal of toxicology 0
mohammad hossein hesami department of pharmacology and toxicology, isfahan university of medical sciences, isfahan, iran. , seyed ebrahim sajjadi department of pharmacology, isfahan university of medical sciences, isfahan, iran. ali hosseini-sharifabad department of pharmacology and toxicology, isfahan university of medical sciences, isfahan, iran.

background: mentha longifolia is one of the aromatic medicinal plant belongs to lamiaceae family. there are some active ingredients in the essential oil of m. longifolia, which potentially could impair the hepatic function. the aim of this study was to find the maximum dose of essential oil of m. longifolia (eoml) that does not show any hepatic deterioration. methods: adult wistar rats fed diff...

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Journal: :Journal of pharmacological and toxicological methods 2013
Jian-Hui He Sheng-Ya Guo Feng Zhu Jun-Jing Zhu Yun-Xiang Chen Chang-Jiang Huang Ji-Min Gao Qiao-Xiang Dong Yao-Xian Xuan Chun-Qi Li

INTRODUCTION Numerous studies have confirmed that zebrafish and mammalian toxicity profiles are strikingly similar and the transparency of larval zebrafish permits direct in vivo assessment of drug toxicity including hepatotoxicity in zebrafish. METHODS Hepatotoxicity of 6 known mammalian hepatotoxic drugs (acetaminophen [APAP], aspirin, tetracycline HCl, sodium valproate, cyclophosphamide an...

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Journal: :Gastroenterology 1980

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Journal: :European Journal of Clinical Pharmacology 2010

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Journal: :Nature 1962

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2012
KRISHAN TEWARI QIN SHI ZHAO Rana Pratap Marg

The present study seeks to evaluate the alcoholic extract of aerial part of H.Sanguinea for its anti-hepatotoxic effect against carbon tetrachloride (CCl4)

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Journal: :Indian journal of physiology and pharmacology 2004
Mudgal Anantrao Kothekar Razvi Syed Ubaid Jugalkishor Bhavarlal Jaju Md Mateenuddin

Blood samples of animals from groups I and II were taken for liver function tests by cardiac puncture under ether anaesthesia Hepatotoxicity due to antitubercular drugs is found to be mediated through oxidative stress and free radical damage to hepatocytes (1, 2, 3). The antioxidants α-tocopherol and selenium are known exert beneficial effect in antitubercular drugs induced hepatotoxicity (4, 5...

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Journal: :Hepatology 2001

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2011
Emeka E.J. Iweala

This preliminary study was undertaken to investigate some biochemical and histological effects of consumption of Talinum triangulare (L.) Juss – supplemented diet in hepatotoxic rats in which liver damage was induced with paracetamol. Thirty female rats were divided into six groups of five rats per group for control, hepatotoxic and non-hepatotoxic groups and were fed 5% or 10% T. triangulare-s...

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Journal: :Acta medica portuguesa 1984
M Camilleri R M Victorino H J Hodgson

A 33 year old woman developed a florid form of chronic active hepatitis after exposure to halothane. Histological and immunological data suggested that autoimmune type chronic active hepatitis antedated the acute hepatotoxic sequelae of the hatothane anaesthesia. Studies on the immuno regulatory functions of peripheral blood lymphocytes revealed a marked defect in suppressor cell function. It i...

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