نتایج جستجو برای: hepatotoxic

تعداد نتایج: 1645  

Journal: :Hepatology 2001

2011
Emeka E.J. Iweala

This preliminary study was undertaken to investigate some biochemical and histological effects of consumption of Talinum triangulare (L.) Juss – supplemented diet in hepatotoxic rats in which liver damage was induced with paracetamol. Thirty female rats were divided into six groups of five rats per group for control, hepatotoxic and non-hepatotoxic groups and were fed 5% or 10% T. triangulare-s...

Journal: :Journal of pharmacological and toxicological methods 2013
Jian-Hui He Sheng-Ya Guo Feng Zhu Jun-Jing Zhu Yun-Xiang Chen Chang-Jiang Huang Ji-Min Gao Qiao-Xiang Dong Yao-Xian Xuan Chun-Qi Li

INTRODUCTION Numerous studies have confirmed that zebrafish and mammalian toxicity profiles are strikingly similar and the transparency of larval zebrafish permits direct in vivo assessment of drug toxicity including hepatotoxicity in zebrafish. METHODS Hepatotoxicity of 6 known mammalian hepatotoxic drugs (acetaminophen [APAP], aspirin, tetracycline HCl, sodium valproate, cyclophosphamide an...

Journal: :Environmental Health Perspectives 1976

Journal: :Gastroenterology 1968

Journal: :Archives of Neurology 2000

Journal: :Environmental Health Perspectives 1976
J E Gray

Philosophic concepts and pragmatic approaches toward improved understanding of the effect of drugs in the hepatocyte are reviewed. No set pattern of studies is advocated but rather observations are encouraged within the framework of studies that provide for varied exposure of the hepatocyte. Clinical usage should be imitated to provide earliest possible indications of toxicity in man. The need ...

Journal: :iranian journal of toxicology 0
mohammad hossein hesami department of pharmacology and toxicology, isfahan university of medical sciences, isfahan, iran. , seyed ebrahim sajjadi department of pharmacology, isfahan university of medical sciences, isfahan, iran. ali hosseini-sharifabad department of pharmacology and toxicology, isfahan university of medical sciences, isfahan, iran.

background: mentha longifolia is one of the aromatic medicinal plant belongs to lamiaceae family. there are some active ingredients in the essential oil of m. longifolia, which potentially could impair the hepatic function. the aim of this study was to find the maximum dose of essential oil of m. longifolia (eoml) that does not show any hepatic deterioration. methods: adult wistar rats fed diff...

Journal: :iranian journal of applied animal science 2015
n. bhaskar l. shahani

we studied the hepatotoxic effects of a deltamethrin containing formulation (decis®) on developing em-bryo of gallus domesticus. fertilized eggs were immersed in three different concentrations of deltamethrin (12.5, 25 and 50 mg/l) for 60 min at 37 ˚c prior to incubation (ed 0) and on the 4th day of incubation (ed 4) and incubated till embryonic day (ed) 16. exposure to 50 mg/l of deltamethrin ...

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