Hepatosplenic candidiasis is a fungal infection, which mostly affects patientswith hematologic malignancies such as leukemia. The pathogenesis of thisinfection is not clear yet, and the liver is the most commonly affected organ.Diagnosis of hepatosplenic candidiasis can be only established via biopsy,since computed tomography (CT) scan, ultrasonography, and magneticresonance imaging (MRI) yield...

hepatosplenic candidiasis is a fungal infection, which mostly affects patientswith hematologic malignancies such as leukemia. the pathogenesis of thisinfection is not clear yet, and the liver is the most commonly affected organ.diagnosis of hepatosplenic candidiasis can be only established via biopsy,since computed tomography (ct) scan, ultrasonography, and magneticresonance imaging (mri) yield...

The incidence of hepatic candidiasis is difficult to estimate because of diagnostic difficulties. Its frequency was 7% in a study of 562 adult patients with leukaemia [1]. Hepatic candidiasis (HC), also referred to as chronic disseminated candidiasis, hepatosplenic candidiasis and granulomatous hepatic candidiasis, affects almost exclusively patients undergoing remission induction chemotherapy ...

To determine whether a prior history of hepatosplenic candidiasis resulted in increased Candida-associated morbidity and mortality after marrow transplant, 15 consecutive patients with biopsy-proven hepatosplenic candidiasis were observed prospectively. All patients received amphotericin B before transplant. Amphotericin B was continued at a dose of 0.5 mg/kg/day from conditioning through marro...

Hepatosplenic candidiasis is a fungal infection, which mostly affects patients with hematologic malignancies such as leukemia. The pathogenesis of this infection is not clear yet, and the liver is the most commonly affected organ. Diagnosis of hepatosplenic candidiasis can be only established via biopsy, since computed tomography (CT) scan, ultrasonography, and magnetic resonance imaging (MRI) ...

PURPOSE To determine if fluconazole is effective treatment for hepatosplenic candidiasis that has not resolved with amphotericin B and flucytosine treatment. PATIENTS AND METHODS Six patients (ages 3 to 44) with acute leukemia and hepatosplenic candidiasis who did not respond to prior antifungal therapy were treated with fluconazole. RESULTS All six patients had fever and three had nausea a...

Hepatic or splenic involvement of tuberculosis without other disseminated lesions is a very uncommon form of extrapulmonary tuberculosis, especially in an immunocompetent adult. We report a case of a 25 year-old-man who developed primary hepatosplenic tuberculosis not associated with the lung or other distant organs. He was initially diagnosed with esophageal candidiasis in local clinic. A comp...