introduction and aims: in order to prevent liver cirrhosis and hepatocellular carcinoma in later life, it is essential to prevent hepatitis b virus (hbv) infection in infants. despite the availability of an effective vaccine, hepatitis b still continues to be a significant health problem. the aim of this study is to reveal the efficacy of passive and active immunoprophylaxis for preventing peri...

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conclusions hepatitis b core antibody immunoglobulin m positivity is different in healthy blood donors of different countries according to the prevalence of chronic hepatitis b and its vaccination. based on the current study findings, all positive samples of hepatitis b core antibody in iranian blood banks should be considered as candidates for occult hepatitis b not just the window period infe...

BACKGROUND AND PURPOSE Major hepatotropic viruses continue to be important causes of acute viral hepatitis in developing countries. This work was carried out to detect the seroprevalence of hepatitis E virus (HEV) markers in children with acute viral hepatitis due to hepatotropic viruses (A, B and C) and non-A, non-B, non-C acute hepatitis, and to ascertain the influence of HEV superinfection i...

Abbreviations: FCH, fibrosing cholestatic hepatitis; HAV, hepatitis A virus; HBIG, hepatitis B immunoglobulin; HBV, hepatitis B virus; HCC, hepatocellular carcinoma; HCV, hepatitis C virus; HCV-R, HCV recurrence; HDV, hepatitis D virus; HEV, hepatitis E virus; HVPG, hepatic venous pressure gradient; IgM, immunoglobulin M; LADR, low accelerated dose regimen; LAM, lamivudine; IFNa , interferon al...

BACKGROUND Hepatitis B vaccine and hepatitis B immunoglobulin are considered for newborn infants of HBsAg-positive mothers to prevent hepatitis B infection. OBJECTIVES To assess the beneficial and harmful effects of hepatitis B vaccines and hepatitis B immunoglobulin in newborn infants of HBsAg-positive mothers. SEARCH STRATEGY Trials were identified through The Cochrane Neonatal Group Cont...

OBJECTIVE To evaluate the effects of hepatitis B vaccine and immunoglobulin in newborn infants of mothers positive for hepatitis B surface antigen. DESIGN Systematic review and meta-analysis of randomised clinical trials. DATA SOURCES Electronic databases and hand searches. REVIEW METHODS Randomised clinical trials were assessed for methodological quality. Meta-analysis was undertaken on ...

Background: Scleroderma is a chronic systemic disorder that affects the connective tissues. It is characterized by several immune manifestations, inflammation, vascular damage, and fibrosis. Some of the viral infections with complex mechanisms are involved in the development and progression of many autoimmune diseases, such as scleroderma. The present study aimed to investigate the serological ...