Background: In Iran scince 1992, hepatitis B vaccination was a part of the national vaccination program. Hepatitis B vaccination is effective in the epidemiology of hepatitis B. The aim ofthis study was to evaluate the long – term persistence of immunity. Methods: This cross-sectional analytical study was conducted on children and adolescents aged between 6-18 years in Birjand, who recei...

Background & Aims: Hepatitis B virus is one of the causes of acute and chronic hepatitis. Due to multiple hospitalization and blood transfusion, thalassaemic patients are at higher risk of this infection. Duration of the immunity after vaccination in this high-risk group and the need for booster vaccination is uncertain. The aim of this study was to find antibody titration and immunity to Hepat...

conclusions the results showed a declining trend in anti-hbsab titers over the time after vaccination against hepatitis b virus in our region. further studies are warranted to establish the need for a booster dose in cases that are at risk of hepatitis b virus infection. results hepatitis b seroprotection rates (anti hbsab ≥ 10 iu/l) among vaccinated children and adolescents aged 1 and 18 years...

hepatitis b is the most common cause of acute and chronic viral hepatitis in iran. it is the etiology of 70% of end-stage liver disease and hepatocellular carcinoma in the country. before the universal neonatal vaccination in iran (1992), the contact rate with hbv was about 30% and the hbs ag+ rate was about 3%. in 2009 the contact rate has declined to 18% and hbsag+ rate decreased to 2%. the e...

background: hepatitis- b infection is one of the infectious diseases that transmits via blood transfiosion, blood product, injection, mother to fetus and sexual contact. protective anti hepatitis-b titer are observed in more than 90% of healthy children. the aim of this study was to evaluate seroconversion rates in children who received routine vaccination program. methods: a cross sectional st...

background: hepatitis b virus (hbv) vaccination is a well-known, safe and effective way for protection against hbv infection; however, non-responders remain susceptible to infection with hbv. this is so important in patients with any kind of chronic liver disease, especially chronic hepatitis c virus (hcv) patients in whom acute hbv infection may lead to decompensation of liver disease. some of...

background influenza can causes morbidity and mortality that are greatly enhanced in patients with underlying chronic diseases such as cirrhotic patients. this study was performed to assess the immunogenicity of influenza vaccination in patients with cirrhosis and inactive carriers of hepatitis b virus infection. methods in this clinical study 93 enrolled subjects divided into 3 groups: cirrhot...