introduction and aims: in order to prevent liver cirrhosis and hepatocellular carcinoma in later life, it is essential to prevent hepatitis b virus (hbv) infection in infants. despite the availability of an effective vaccine, hepatitis b still continues to be a significant health problem. the aim of this study is to reveal the efficacy of passive and active immunoprophylaxis for preventing peri...

conclusions hepatitis b core antibody immunoglobulin m positivity is different in healthy blood donors of different countries according to the prevalence of chronic hepatitis b and its vaccination. based on the current study findings, all positive samples of hepatitis b core antibody in iranian blood banks should be considered as candidates for occult hepatitis b not just the window period infe...

BACKGROUND Hepatitis B vaccine and hepatitis B immunoglobulin are considered for newborn infants of HBsAg-positive mothers to prevent hepatitis B infection. OBJECTIVES To assess the beneficial and harmful effects of hepatitis B vaccines and hepatitis B immunoglobulin in newborn infants of HBsAg-positive mothers. SEARCH STRATEGY Trials were identified through The Cochrane Neonatal Group Cont...

OBJECTIVE To evaluate the effects of hepatitis B vaccine and immunoglobulin in newborn infants of mothers positive for hepatitis B surface antigen. DESIGN Systematic review and meta-analysis of randomised clinical trials. DATA SOURCES Electronic databases and hand searches. REVIEW METHODS Randomised clinical trials were assessed for methodological quality. Meta-analysis was undertaken on ...

hepatitis b vaccination is safe and effective, although breakthrough infection occasionally occurs in those who receive the vaccine and hepatitis b immunoglobulin (hbig) prophylaxis. sequence variation in their antigenic regions is one of the most powerful strategies that are used by viruses to escape recognition by b and t cell-mediated immune responses. the aim of this study was to explore th...

celiac disease has been associated with other autoimmune disorders such as autoimmune hepatitis, moreover it is known that t cell mediated immune response to dietary gluten and released cytokines are important for the entheropathy seen in celiac disease. we investigated celiac autoantibodies in patients with autoimmune hepatitis (aih), and chronic hepatitis b (chb). sera from 84 patients with a...

Using the Staphylococcus aureus absorption method, we have modified a commercial radioimmunoassay kit for the determination of total antibody to hepatitis B core antigen so that we can now determine the predominant globulin species of that antibody. One-hundred percent of acute hepatitis B sera had a predominance of immunoglobulin M antibody to hepatitis B core antigen, whereas immunoglobulin G...

0

Abbreviations: FCH, fibrosing cholestatic hepatitis; HAV, hepatitis A virus; HBIG, hepatitis B immunoglobulin; HBV, hepatitis B virus; HCC, hepatocellular carcinoma; HCV, hepatitis C virus; HCV-R, HCV recurrence; HDV, hepatitis D virus; HEV, hepatitis E virus; HVPG, hepatic venous pressure gradient; IgM, immunoglobulin M; LADR, low accelerated dose regimen; LAM, lamivudine; IFNa , interferon al...

BACKGROUND AND PURPOSE Major hepatotropic viruses continue to be important causes of acute viral hepatitis in developing countries. This work was carried out to detect the seroprevalence of hepatitis E virus (HEV) markers in children with acute viral hepatitis due to hepatotropic viruses (A, B and C) and non-A, non-B, non-C acute hepatitis, and to ascertain the influence of HEV superinfection i...