conclusions capillaria hepatica should be considered in differential diagnoses in any child with fever, hepatomegaly, eosinophilia and hyperglobulinemia. case presentation the current paper reports a case of capillaria hepatica infection in a four-year-old boy which presented with fever, hepatomegaly, peripheral eosinophilia, and noticeable weight loss. the diagnosis was made on the histologica...

chronic granulomatous disease (cgd) is a rare inherited disorder characterized by inability of phagocytes to generate oxygen radicals needed for intracellular killing of phagocytic microorganisms. we report a 2.5-year-old iranian female with multiple liver abscesses. she was admitted in surgical ward because of abdominal pain and fever for one month duration that had no response to conventional...

Background & Aims: Granulomatous phlebitis of hepatic vein is a rare disease and its exact etiopathogenesis remains unknown. Recently, we experienced granulomatous phlebitis of small hepatic veins in a patient who underwent hepatic resection for metastatic liver cancer after preoperative portal venous embolization (PVE). Methods: We surveyed such phlebitis in the patients who underwent PVE (200...

The egg-induced granulomatous reaction in Schistosoma mansoni-infected individuals develops within the portal system of the liver and is the major pathological finding in schistosomiasis. We have infected mice lacking the gamma interferon (IFN-gamma) receptor with S. mansoni larvae and studied the development of hepatic granulomas in these mutant mice in comparison to that in control wild-type ...

Extracts prepared from tissue with granulomatous inflammation experimentally produced in liver of CBA-strain mice showed increased hydrolysis of leukotriene D4 (LTD4), Leu-Leu and Ala-Gly as compared with normal hepatic cells. Two dipeptidases, Leu-Leu dipeptidase and Ala-Gly dipeptidase, were purified from hepatic granulomas, and quantitative conversion of LTD4 into leukotriene E4 (LTE4) by bo...

Since the advent of stapedotomy and its use in the treatment of otosclerosis, a few complications have been reported in the literature. Among them, the granulomatous reaction, described by Harris and Weiss in 1962, is rare. It is an excessive inflammation that forms granulation tissue around the prosthesis and the oval windows. Although the etiology is uncertain, several authors believe that th...

in patients with malignancy, the common etiologies of granuloma formation are tumor related sarcoid reaction, sarcoidosis, tuberculosis and other granulomatous diseases. often, the finding of granulomas in malignant patients may obscure the primary malignancy or may mislead towards treatment of infectious and other etiologies. hence, their proper recognition and necessary follow up is needed to...

Human abdominal angiostrongyliasis is a zoonotic disease caused by ingestion of the L3 larvae of Angiostrongylus costaricensis. The human infection gives rise to a pathological condition characterized by acute abdominal pain, secondary to an inflammatory granulomatous reaction, marked eosinophilia and eosinophilic vasculitis. Most commonly this disease is limited to intestinal location, primary...

Intravesical instillation of Bacillus Calmette-Guerin (BCG) hasbecome an established adjuvant treatment for superficial bladdercarcinoma. This treatment is associated with a relatively high rateof side effects which are mostly reversible spontaneously or canbe treated symptomatically. Serious systemic side effects are lessfrequent. One of rare complications is gran...