background: bone marrow transplantation is a good therapeutic modality for beta thalassemia. liver complications is one of the major causes of morbidity and mortality following bmt. determination of the factors of liver injury leads to earlier diagnosis after bmt and improves prognosis. materials and methods: we studied 113 major beta thalassemic patients who have been transplanted from 1990- 2...

conclusions despite the adverse effects of inhalational halogenated anesthetics (especially halothane) on hepatic patients when necessary. the effects on all systems must be considered and the necessary preparations must be provided. these drugs are still used, if necessary, due to the presence of positive effects and advantages mentioned in other studies as well as the adverse effects of other...

conclusions a review of the literature on the use of hypnotic drugs in patients with liver dysfunction showed that some hypnotic drugs used during anesthesia could be safely used in patients with impaired liver function. in these patients, certain drugs should be used with caution. results anesthesia should be performed with caution in patients with hepatic dysfunction and drugs with long half-...

background: renal complication of leptospirosis is common and its clinical manifestations vary from urinary sediment changes to acute renal failure. the aim of this study was to determine the final outcome of renal involvement in leptospirosis. methods: this longitudinal prospective study included all serologically confirmed cases of leptospirosis with evidence of renal failure. all patients we...

context patients with hepatic dysfunction suffer from many problems and associated complications in organs other than the liver. therefore, it is very important to investigate the effects of different drugs in the treatment of these patients. due to the high consumption of non-steroidal anti-inflammatory drugs (nsaids), studying the effects of these drugs in patients with hepatic dysfunction is...

introduction: bone marrow transplantation is a good therapeutic modality for beta thalassemia. liver complications are one of the major causes of morbidity and mortality following bmt. determination of the factors of liver injury leads to earlier  diagnosis after bmt and improves prognosis. method: we studied 113 major beta thalassemic patients who have been transplanted from 1990- 2000 in bone...

Introduction: Cadmium chloride causes hepatic dysfunction. In the present study, the protective effects of hydroalcoholic extract of Alcea rosea aerial parts were investigated on the hepatic enzyme dysfunction induced by cadmium chloride in adult male rats. Method: In this experimental study, 54 adult male Wistar rats were divided into six groups of 9 as follows; control group, sham group 1 re...

Regular packed cell transfusion in patients with thalassemia major leads to iron overload. Chelation therapy is one of the important aspects of thalassemia care as iron overload causes significant cardiac, hepatic, and endocrine dysfunction. We report a case of thalassemia major with severe iron overload causing cardiac and liver dysfunction who benefitted from triple drug chelation therapy. Tr...