نتایج جستجو برای: hemoglobin f

تعداد نتایج: 360598  

Journal: :The Korean Journal of Hematology 2011

2011
Akanni E. Olufemi Oseni B. Sola Bamisaye E. Oluwaseyi Raji A. Ajani Mewoyeka O. Olusoji Hassan R. Olubunmi

BACKGROUND Fetal hemoglobin (HbF) levels in different hemoglobin variants in Osogbo, Nigeria, were estimated using two principal methods of estimation using existing information for HbF concentration and distribution of various hemoglobin variants in the area, as well as diagnosed cases of thalassemia. Two hundred and sixty samples collected from HbSS, HbSC, HbAA, HbAS, and HbAC subjects were a...

Journal: :international journal of hematology-oncology and stem cell research 0
majid farshdousti hagh division of laboratory hematology and blood banking, faculty of medicine, tabriz university of medical sciences, tabrez, iran ali dehghani fard department of hematology and blood banking, faculty of medical sciences, tarbiat modares university,tehran, iran najmaldin saki research center of thalassemia and hemoglobinopathies, ahvaz jundishapur university of medical sciences, ahvaz, iran mohammad shahjahani department of hematology and blood banking, faculty of medical sciences, tarbiat modares university,tehran, iran saied kaviani department of hematology and blood banking, faculty of medical sciences, tarbiat modares university,tehran, iran

hemoglobin f (hbf, α 2 γ 2 ) is a major contributor to the clinical heterogeneity and ameliorating agent observed in patients with the β-globin disorders including β-thalassemia and sickle cell disease (scd). during fetal life, hbf is the major hemoglobin but is largely substituted by adult hemoglobin (hba, α 2 β 2 ) following a globin expression switch after birth. increased γ-globin expressio...

Journal: :Van Medical Journal 2016

2002
Kazuhiko Adachi Jian Pang

To further understand determinants for Hemoglobin (Hb) S polymerization, as well as the inhibitory mechanism of Hb F on Hb S polymerization, Hb F variants containing Val-* (Hb F yE6V) or Val-*, Thr-y87 (Hb F yE6V. yQ87Tj were expressed in yeast. The oxy form of Hb F yE6V was about 10-fold less stable to mechanical agitation than native oxy Hb F, which is similar to stability differences compari...

Journal: :international journal of hematology-oncology and stem cell research 0
ebrahim miri-moghaddam associate professor, ph.d in human molecular genetics, department of genetics, faculty of medicine, birjand university of medical sciences, birjand, iran sara bahrami msc in biology, department of biology, payame noor university, iran majid naderi associate professor, genetics of non-communicable disease research center, department of pediatric hematology & oncology, faculty of medicine, zahedan university of medical sciences, zahedan, iran ali bazi msc in hematology, faculty of allied medical sciences, zabol university of medical sciences, zabol, iran morteza karimipoor ph.d, molecular medicine department, biotechnology research center, pasteur institute of iran, tehran, iran

background: xmn-1 polymorphism of

Journal: :Blood 2009
Victor R Gordeuk Andrew Campbell Sohail Rana Mehdi Nouraie Xiaomei Niu Caterina P Minniti Craig Sable Deepika Darbari Niti Dham Onyinye Onyekwere Tatiana Ammosova Sergei Nekhai Gregory J Kato Mark T Gladwin Oswaldo L Castro

Hydroxyurea and higher hemoglobin F improve the clinical course and survival in sickle cell disease, but their roles in protecting from pulmonary hypertension are not clear. We studied 399 children and adolescents with sickle cell disease at steady state; 38% were being treated with hydroxyurea. Patients on hydroxyurea had higher hemoglobin concentration and lower values for a hemolytic compone...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید