coefficient (KoA) over a wide range of hemodialysis operating conditions. When QB and QD are low, however, mismatch of these flows within the hemodialyzer creates a shunt in which no solute transfer occurs. In a previous study of nine patients during sustained low-efficiency dialysis, QB of 200 ml/min and QD of 100 ml/min were used with a 1.8 m polysufone low-flux hemodialyzer. Measured Kd for ...

The apparent hemodialyzer elimination rate constant and clearance for gentamicin and tobramycin were determined during 100 routine hemodialysis treatments in 49 patients. Three different dialyzers (CDAK 3500, CF 1211, and CF 1511), which vary in membrane composition, surface area, and thickness, were evaluated. The elimination rate constant in each patient was calculated from the slope of the l...

In this study, a new cost-benefit economic model for hemodialyzer reuse has been developed considering all of the direct costs (dialyzer price, disinfection fluid reverse osmosis water cost, personnel, and miscellaneous) as well number disinfections applied to hemodialyzer. The maximum disinfections/reuses different models was estimated using statistical analysis based on information obtained f...

The success and the quality of hemodialysis therapy are mainly related to both clearance and biocompatibility properties of the artificial membrane packed in the hemodialyzer. Performance of a membrane is strongly influenced by its interaction with the plasma protein repertoire during the extracorporeal procedure. Recognition that a number of medium-high molecular weight solutes, including prot...