background hemolyis of red blood cells is a serious toxic effect commonly found among patients envenomed by hemiscorpius lepturus scorpion. objectives the aim of the present study was to evlaute the efficay of the avaible polyvalent antivneom in preventing this phenomena. materials and methods using a red blood cell fragility test, the anti-hemolytic effectiveness of a new antivenom serum again...

Many of the published accounts of envenomation by Hemiscorpius lepturus (H. lepturus) are in a form that makes it difficult for non Farsi readers to access. The purpose of this review is to summarise the Iranian literature on the toxinological effects of the venom of H. lepturus using both in vivo and in vitro data and where appropriate, details of methods and ethics statements will be reported.

Hemoscorpius lepturus is the most medically important scorpion in Iran. The clinical signs of H. lepturus envenomation are remarkably similar to those reported for brown spiders, including dermonecrosis, hematuria, renal failure and even death. The lethality and toxicity of brown spiders' venom have been attributed to its phospholipase D activity. This study aims to identify a phospholipase D w...

Hemiscorpius lepturus (H. lepturus), found in south-western areas of Iran and south of Iraq, is considered to be the most dangerous scorpion in the region, and poses a significant risk to the health of the indigenous population due to the unique, clinical manifestations associated with its sting.. In the present study, 36 patients from the Khuzestan province in the southwest of Iran, displaying...

BACKGROUND During the recent years, significant progress has been achieved on development of novel anti-viral drugs. Natural products are assumed as the potential sources of novel anti-viral drugs; therefore, there are some previous studies reporting the anti-viral compounds from venomous animals. Based on the significant value for tracing of non-toxic anti-viral agents from natural resources, ...

Hemiscorpius lepturus (H. lepturus) is one of the most dangerous scorpions in Iran. Intramuscular administration (IM) of available Razi antivenom to H. lepturus venom is used by many of Iranian clinicians. The purpose of the current study was to investigate the efficiency of IM route for treatment of envenomed patients by H. lepturus. We compared the pharmacokinetics parameters of venom and ant...

Scorpion stings are common in Iran, particularly in the southern and southwest regions of the country, and they pose a serious health problem. Hemiscorpius lepturus is the most venomous scorpion in the region. The present study was conducted to investigate the in vivo effects of scorpion venom in experimental mice. Haematological parameters (white and red blood cells numbers and haematocrit lev...

This work aimed to study the temporal variation of metazoan parasites of Trichiurus lepturus from the coastal zone of Rio de Janeiro, Brazil. Between July 2006 and June 2007, there were four seasonal quarterly samples of 30 specimens of T. lepturus. In addition to a group composed of anisakid larvae, we collected a total of 14 species of metazoan parasites: five digenean; five monogenean, two c...

BACKGROUND Envenomation by Hemiscorpius lepturus is not painful and the clinical manifestations include bloody urine due to hemoglobinuria or hematuria, dermonecrotic reactions, cardiac arrhythmia and in minority of cases acute renal failure which may lead to death following disseminated intravascular coagulation in infants. Cardiac effects of envenomation by H. lepturus venom including inotrop...

It is observed that some venom may have an anticancer effect. Hemiscorpius lepturus is a most dangerous scorpion in Iran. Heminecrolysin is the most toxic fraction of Hemiscorpius lepturus venom and it is responsible for hemolytic effects of the venom. In this research, we purified heminecrolysin by FPLC, and HPLC methods and used MTT assay in prostatic cancer cell line (PC3 cells). We observed...