Evidence on risk factors for Clostridium difficile infection (CDI) in hemato-oncologic patients is conflicting. We studied risk factors for CDI in a large, well-characterized cohort of hemato-oncological patients. 144 hemato-oncological patients were identified in this retrospective, single center study with a microbiologically confirmed CDI-associated diarrhea. Patients were compared with 144 ...

INTRODUCTION The paucity of data on resource use in critically ill patients with hematological malignancy and on these patients' perceived poor outcome can lead to uncertainty over the extent to which intensive care treatment is appropriate. The aim of the present study was to assess the amount of intensive care resources needed for, and the effect of treatment of, hemato-oncological patients i...

Clinic of Pediatric Hemato-Oncology, Department of Woman’s and Children’s Health, Surgical Pathology and Cytopathology Unit, Department of Medicine, and First Medical Clinic, Department of Medicine, University of Padua, Padua, Italy; Hematopathology Unit, Sant’Orsola-Malpighi Hospital, Bologna, Italy; Department of Hemato-Oncology, Gaslini Institute, Genova, Italy; Pediatric Hematology and Onco...

AIM The aim was to determine hemato-biochemical alterations and to determine the better treatment of theileriosis in naturally infected calves. MATERIALS AND METHODS A total of 74 Holstein crossbred calves below 6 months of age, of either sex were included for present investigation in Bikaner. Based on the clinical examinations and laboratory results, 20 calves included for hemato-biochemical...

Hypnale hypnale (hump-nosed pit viper) is a medically important venomous snake in Sri Lanka and Southwestern India. Bite of this snake may result in hemostatic dysfunction, acute kidney injury and death. Clinical studies indicated that the locally available polyvalent antivenoms produced in India are not effective against hump-nosed pit viper envenoming. Hence, there is an urgent need to search...

Dried blood spot (DBS) sampling for the purpose of therapeutic drug monitoring can be an attractive alternative for conventional blood sampling, especially in children. This study aimed to compare all costs involved in conventional sampling versus DBS home sampling in two pediatric populations: renal transplant patients and hemato-oncology patients. Total costs were computed from a societal per...

Occurrence of vancomycin-resistant enterococci and its relationship to the administration of glycopeptide antibiotics (vancomycin, teicoplanin) was described. A total number of 628 strains of the genus Enterococcus was isolated in the Hemato-oncologic Department of the University Hospital in Olomouc in 1997. Seven strains (1.1%) were found to be resistant to vancomycin. Five of them were identi...

Therapy with the use of chimeric antigen receptor T-cell (CAR T-cells) is one most modern medical technologies in hemato-oncology, using, thanks to advances molecular biology, natural anti-cancer immune mechanisms. Nowadays, it an extremely effective complement conventional treatment and hematopoietic cell transplantation. Ongoing clinical trials show enormous potential this beyond hemato-oncol...