altered glycosylation of proteins in cancer cells is one of the main processes responsible for anaplasia, invasion and metastatic potential of neoplastic cells. lectins are nonimmunogenetic compounds which specifically detect certain terminal sugars of glycoconjugates. the aim of the present study was to identify the n-acetylgalactosamine (galnac) containing glycoconjugates in cancer cells in a...

bioactive products from snail slime of “helix” specie have potential applications in preventing and/or treating several human diseases and in cancer diagnosis. however, the poor pharmacokinetics characteristics of these natural compounds limit their use. nanotechnology offers promising solutions for the enhanced formulation of these molecules through the synthesis of nanosized drug delivery sys...

[this article has been retracted for duplicate publication] background: the pathological classification of cryptogenic fibrosing alveolitis has been a matter of debate and controversy for histopathologists. objective: to identify and specify the glycotypes of capillary endothelial cells in usual interstitial pneumonia (uip) compared to those found in normal tissue. methods: sections of formalin...

The aim of the present study was to investigate the changes in the localisation of glycoconjugates caused by 5-minute-long ischaemia as a consequence of bilateral ligation of common carotid arteries. Histochemical evaluation was performed using specific lectins that recognize the following sugar residues: 1) alpha-D-galactosyl and N-acetylgalactosaminyl (Bandeiraea simplicifolia agglutinin, BS-...

The accuracy and sensitivity of PCR-based methods for detection of hepatitis A virus (HAV) are dependent on the methods used to separate and concentrate the HAV from the infected cells. The pH and ionic strength affect the binding affinity of the virus to cells. In this study, we initially investigated the effects of pH (4.0-10.0) and metal ions (Fe²⁺, Co²⁺, Cu²⁺, Mg²⁺, K⁺, and Ca²⁺) on the bin...