Nuclear accumulation ofp53 protein Is associated with a poorer clinical outcome in breast cancer patients. Heat shock protein 70 (lssp7O) is a chaperone that binds to mutant p53 and consequently could regulate its accumulation or localization. The aims of this study were to determine if the prognostic significance ofp53 accumulation was dependent on the type ofantibody used for detection and wh...

Changes in tree species distributions are a potential impact of climate change on forest ecosystems. The examination of tree species shifts in forests of the eastern United States largely has been limited to simulation activities due to a lack of consistent, long-term forest inventory datasets. The goal of this study was to compare current geographic distributions of tree seedlings (trees with ...

The p53 tumor suppressor protein is an important regulator of cell proliferation and apoptosis. p53 can be found in the nucleus and in the cytosol, and the subcellular location is key to control p53 function. In this work, we found that a widely used monoclonal antibody against p53, termed Pab 1801 (Pan antibody 1801) yields a remarkable punctate signal in the cytoplasm of several cell lines of...

PURPOSE Determining the ideal length of a ureteric stent is important to avoid complications associated with stent placement. Clinically, most urologists usually choose the length of a ureteric stent according to the patient's height. On the basis of a Chinese population study, a 22 cm ureteric stent has been recommended for patients smaller than 175 cm. We evaluated the appropriateness of this...

BACKGROUND Clinical determination of mid-parental height is an important part of the assessment of a child's growth, however our clinical impression has been that parents cannot be relied upon to accurately report their own heights. Therefore, we conducted this study to assess the accuracy of parental height self-reporting and its effect on calculated mid-parental target height for children pre...

Longitudinal standards for height and height velocity are essential to monitor for appropriate linear growth. We aimed to construct standards in Korean children and adolescents through the population-based longitudinal Kangwha study. Our study was a part of a community-based prospective cohort study from 1986 to 1999 with 800 school children. Height and height velocity were recorded annually fr...

In order to standardize the results of different biomechanical studies concerning stresses on lumbar discs, it may be useful to estimate the disc dimensions of the examined subjects and to refer the stress values to a unit surface area (square centimeter). The association between anthropometric parameters and discal areas at the L3-L4, L4-L5 and L5-S1 levels, examined by computed axial tomograp...

background: dystocia is one of the important causes of maternal morbidity and mortality in low-income countries. this study wasaimed to determine the diagnostic accuracy of maternal anthropometric measurements as predictors for dystocia in nulliparous women. materials and methods: this prospective cohort study was conducted on 447 nulliparous women who referred to omolbaninhospital. several mat...