long-term mechanical circulatory support is a life-saving technology while briding to heart transplantation. it increases the quality of life and preserves end-organ function for patients with  advanced heart failure. the number of patients with advanced heart failure scheduled for heart transplantation before comorbidities escalate is on the rise. however, the device function is complicated by...

conclusions the cardiac grafts at 5 months' post-htx follow-up were characterized by normal lv dimensions and ef. also, rv dysfunction and tricuspid regurgitation were frequent findings, but they were not associated with the clinical signs of congestive heart failure, morbidity, and mortality in the majority of our patients. background in patients with advanced heart failure, significant improv...

heart failure is common in patients with chronic renal disease, either as a complication of renal failure or from shared risk factors, or is the major cause of death in patients on dialysis. at present, end stage renal disease (esrd) patients who have systolic heart failure are considered high-risk for surgery; and nephrologists and cardiologists are reluctant to refer these patients for kidney...

background and objective: sleep-disordered breathing (sdb) is associated with increased morbidity and mortality in patients with heart failure (hf). we assessed the prevalence and the pattern of sdb in hf patients who were candidates for heart transplantation. materials and methods: twenty heart transplantation patients with ventricular ejection-fraction < 25% were recruited consecutively in a ...

background: recently, stem cells have been considered for the treatment of heart diseases, but no marked improvement has been recorded. this is the first study to examine the functional and histological effects of the transplantation of human amniotic mesenchymal stromal cells (hamscs) in rats with heart failure (hf). methods: this study was conducted in the years 2014 and 2015. 35 male wistar ...

major complications of heart transplantation include graft rejection, infection, graft arteriosclerosis, malignancy, and drug toxicity. among these complications, infections and thrombophilic disorders are of particular interest owing to their major contribution to morbidity and mortality among heart transplantation patients. thrombophilic disorders are caused by imbalance between hypercoagulat...

post cardiac surgery ophthalmic complications are uncommon, and sudden visual loss is one of the most important ophthalmic problems in these patients. we report a 54-year-old woman that suffered transient sudden bilateral visual loss seven days after orthotopic heart transplantation. in ophthalmologic examination positive findings were bilateral normal size pupils without direct and indirect pu...

Heart failure is one of the leading causes of death worldwide. End stage disease often requires heart transplantation, which is hampered by donor organ shortage. Tissue engineering represents a promising alternative approach for cardiac repair. For the generation of artificial heart muscle tissue several cell types, scaffold materials and bioreactor designs are under investigation. In this revi...

Heart failure, a complex cardiovascular condition, is huge burden on patients, caregivers, and healthcare systems it prevalent worldwide. failure caused by wide variety of underlying conditions that include both cardiac non-cardiac pathologies. Identifying the cause enables us to apply etiology-based interventions. The spectrum heart management ranges from classification transplantation. In add...