in this study a new minimum lumped electrical model of total circulatory system through numerical solutions to approximate the response of the human circulatory system was presented. among five existent ventricular elastances as activity function of heart pumps, a more accurate model was chosen as well as the operation of baroreflex system to accommodate variations in heart rate and systemic va...

heart failure (hf) is still a major problem worldwide with high morbidity and mortality rates. the recently developed medication for hf is still incapable of reducing its morbidity and mortality, and clinical data supporting the efficacy and safety of its mainstay therapy remain insufficient. arginine-vasopressin (avp) plays important roles in circulatory and water homeostasis, one of which is ...

Background: Heart failure (HF) has become one of the most prevalent cardiovascular problems worldwide. Considering the beneficial effects of probiotics on human health, we aimed to investigate the anti-inflammatory effect of oral administration of Lactobacillus paracasei in HF induced by isoproterenol. Methods: Forty Wistar male rats weighing 80g on average were randomly assigned to five grou...

background: recently, stem cells have been considered for the treatment of heart diseases, but no marked improvement has been recorded. this is the first study to examine the functional and histological effects of the transplantation of human amniotic mesenchymal stromal cells (hamscs) in rats with heart failure (hf). methods: this study was conducted in the years 2014 and 2015. 35 male wistar ...

conclusions: thus, identifying the hf patients before the flight and providing them proper education about the events that may occur during flight is necessary. results: hf patients are more prone to experience respiratory distress, anxiety, stress, cardiac decompensation, and venous thromboembolism (vte) during air travel. although stable hf patients can tolerate air travel, but those with acu...

polyunsaturated fatty acids (pufas) particularly ω-3 pufas showed great assure in prevention of cardiovascular diseases (cvd). the evidence for cv benefits of pufa comes from eicosapentaenoic acid (epa) with or without docosahexaenoic acid (dha) in primary prevention, after myocardial infarction (mi), with heart failure (hf). the epidemiologic studies and trials showing the benefits of pufa, sp...

Objective(s): Existing studies have demonstrated that intravenous and intramyocardial-administrated mesenchymal stem cells (MSCs) lead to tissue repair after cardiac disorders. We compared the efficiency of both administration methods.Materials and Methods: A rat model of isoproterenol-induced heart failure (ISO-HF) was established to co...