BACKGROUND The objective of this review is to determine the effectiveness of Harpagophytum procumbens preparations in the treatment of various forms of musculoskeletal pain. METHODS Several databases and other sources were searched to identify randomized controlled trials, quasi-randomized controlled trials, and controlled clinical trials testing Harpagophytum preparations in adults suffering...

Harpagophytum, Devil's Claw, is a genus of tuberiferous xerophytic plants native to southern Africa. Some of the taxa are appreciated for their medicinal effects and have been traditionally used to relieve symptoms of inflammation. The objectives of this pilot study were to investigate the antioxidant capacity and the content of total phenols, verbascoside, isoverbascoside, and selected iridoid...

The genus Harpagophytum has two species: H. procumbens which is an important medicinal plant in southern Africa, and H. zeyheri. Genetic diversity in 96 samples, obtained by germinating seeds collected from Botswana, was assessed using six inter-simple sequence repeat (ISSR) and 10 random amplified polymorphic DNA (RAPD) primers. These DNA markers yielded a total of 138 polymorphic bands. Polym...

OBJECTIVE To examine systematically the quality of the clinical trials investigating the effectiveness of Harpagophytum products. METHODS Literature searches and enquiries to experts identified 20 studies of treatment with various Harpagophytum products (powder, aqueous and ethanolic extracts) for exacerbations of chronic musculoskeletal pain. Eight were open uncontrolled observational studie...

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Extract of Harpagophytum procumbens (devil's claw) has become the focus of research as a potential therapeutic agent in the treatment of rheumatic arthritis and pain due to its favorable side effects profile compared to synthetic alternatives. This superior safety of treatment is very valuable, especially in view of that in mandatory long duration of therapy in chronic diseases. None of NS...

background: sore throat is one of the major complications of tracheal intubation after general anesthesia. harpagophytum is an herbal medicine, the anti-inflammatory and analgesic effects of which have been demonstrated in various studies. we studied the effects of single dose harpagophytum one hour before tracheal intubation, to prevent the sore throat after extubation. methods: in a randomize...

Coldenia procumbens Linn is a commonly available weed, which is widely used in the codified Indian systems of medicine namely Ayurveda and Sidha. The variety of medical applications of the plant parts and relative lack of enough literature on the pharmacological activities provoke a preliminary study on its various applications including antibacterial activity.

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