The mammalian cochlea is a highly complex structure which contains several cells, including sensory receptor or hair cells. The main function of the cochlear hair cells is to convert the mechanical vibrations of the sound into electrical signals, then these signals travel to the brain along the auditory nerve. Auditory hair cells in some amphibians, reptiles, fish, and birds can regenerate or r...

Background: Low-level lasers are used for various medical applications including wound healing and hair loss treatment. Cell Therapy using skin stem cells could be a novel approach to hair transplantation. However, there is no study on the effect of low-level laser on the hair follicle stem cells. So, in this study, we investigated the effect of low level laser irradiation on viability and ROS ...

Background: One of the key questions in biochemistry is why cell becomes aged and what are the involved factors? Why cell growth is stopped after some divisions and cells become senescent? This occurs in a greater frame in the whole body and cells dye after a while. Androgenetic alopecia (AGA) is characterized by a loss or decrease in hair follicle size, which could be related to the loss of ha...

conclusions fmf should be considered in patients who present with alopecia, acne like lesions, cysts and comedones in older ages with a spectrum of histologic changes. we emphasize for any time it should be under-recognized. introduction folliculotropic mycosis fungoides (fmf) is a variant of mycosis fungoides characterized by the presence of folliculotropic atypical tcells infiltrates, often w...

background many industrial devices have an excessive vibration which can affect human body systems. the effect of vibration on cochlear histology has been as a debatable problem in occupational health and medicine. objectives due to limitation present in human studies, the research was conducted to survey the influence of vibration on cochlear histology in an animal model. materials and methods...

Introduction: Nowadays, cell therapy is the most advanced treatment of peripheral nerve injury. The aim of this study was to determine the effects of transplantation of hair follicle stem cells on the regeneration of the sciatic nerve injury in rats. Methods: The bulge region of the rat whisker was isolated and cultured. Morphological and biological features of the cultured bulge cells were ob...

Despite the significant advances in regenerative medicine, wound healing has remained a challenging clinical problem. Skin is the largest human organ with many vital functions; therefore, any damage to its normal structure should be treated as soon as possible. Easy access to skin stem cells has created a lot of excitement in therapeutic applications. “Cell therapy” is considered a novel method...

we compared the extent of temporary threshold shift (tts) and hair cell loss following high level 4 khz noise exposure with those preconditioned with moderate level 1 and 4 khz octave band noise. fifteen male albino guinea pigs (300- 350 g in weight) were randomly allocated into three groups: those exposed to 4 khz octave band noise at 102 db spl (group 1, n=5); those conditioned with 1 khz oct...