due to some important applications of guanine electrode in scientific and technology research such as electro-chemical dna based biosensors, and a problem of high redox potential of guanine (0.81 v), our research study concentrates on reducing guanine redox potential by substituting cu, ag, au, ch3, c2h5 and cl on sites of 1, 2 and 9 of guanine. a 5.0% reduction of redox potential for 9-ag-guan...

Due to some important applications of guanine electrode in scientific and technology research such as electro-chemical DNA based biosensors, and a problem of high redox potential of guanine (0.81 V), our research study concentrates on reducing guanine redox potential by substituting Cu, Ag, Au, CH3, C2H5 and Cl on sites of 1, 2 and 9 of guanine. A 5.0% reduction...

Xanthine phosphoribosyltransferase (XPRT) and hypoxanthine-guanine (HGPRT) are purine salvaging enzymes of Leishmania donovani with distinct 6-oxopurine specificities. LdXPRT phosphoribosylates xanthine, hypoxanthine, guanine, preference toward whereas LdHGPRT only hypoxanthine guanine. In our study, was used as a model to understand these base Mutating I209 V, the conserved residue found in HG...

We performed a theoretical study, at the BLYP/aug-cc-pVDZ level, of mechanisms H-transfer between biologically relevant tautomers cytosine and guanine. The analysis ground- excited state energy barriers conversions showed that in some cases they are lower as compared to ground reactions. inclusion one water molecule catalyst oxo-amino form guanine drastically changes mechanism reactions well st...

AbstractWe investigate the solubility of guanine and uracil, two nucleic acid bases xylose, glucose, sucrose solutions in aqueous, It was discovered Guanine rises lockstep with glucose concentrations, However, this is not case for other reagents. increases below 1.5M reagent, it follows pattern: ribose(R)

two capillary zone electrophoresis (cze) methods were developed in this study, one using an acidic buffer (sodium citrate ph = 2.5) and the other using a basic buffer (sodium tetraborate ph = 9.8). the two methods were compared on the basis of repeatability and reproducibility of results and the cze method developed with the basic buffer was then selected for further studies. the method was ful...

the hydration of biomolecules is vitally important in molecular biology, so in this paper thesolvation energy and radial distribution function of dna bases have been calculated by themonte carlo simulation.the geometries of isolated adenine, guanine, cytosine, and thyminehave been optimized using 6-31+g(d,p) basis function sets. these geometries then will be used inthe monte carlo calculation o...

Dramatic colours and pattern changes in chameleons arise from the optical properties of biogenic guanine nanocrystals

In the present work, the substituent effect on the strength of H-bonds in the guanine – cytosine base pair was studied when the substituents are connected to the guanine base through a phenyl ring. In this study, guanine was substituted in the H8 and H9 positions by electron donating (ED) and electron withdrawing (EW) groups mediated by a phenyl ring in the gas phase. The calculations were perf...