clarithromycin (cla), a broad-spectrum macrolide, is a poorly soluble drug with dissolution rate limited absorption. the aim of this investigation was to prepare cla nanoparticles from a ternary ground mixture in the presence of sodium lauryl sulfate (sls) and polyvinyl pyrrolidone (pvp) as co-grinding water-soluble compounds, in order to improve the drug dissolution rate. different weight rati...

We attempted the development of rapid oral disintegration tablets by direct compression using co-ground mixture of D-mannitol and crospovidone. The co-ground mixture was prepared with a vibration rod mill. The tablets were formed by compression using a single punch-tableting machine after addition of the co-ground mixture to non-ground D-mannitol, crospovidone and magnesium stearate. Regarding ...

One of the most important problems facing land cover mapping effort in Egypt is intensive and mixed landcover areas, which represent the majority of agricultural productive areas. This study was carried out to evaluate the possibility of using Linear Mixture Model as a sub pixel classification technique to extract fraction images from Landsat Enhanced Thematic Mapper data, which may help in fut...

Clarithromycin (CLA), a broad-spectrum macrolide, is a poorly soluble drug with dissolution rate limited absorption. The aim of this investigation was to prepare CLA nanoparticles from a ternary ground mixture in the presence of sodium lauryl sulfate (SLS) and polyvinyl pyrrolidone (PVP) as co-grinding water-soluble compounds, in order to improve the drug dissolution rate. Different weight rati...

Clarithromycin (CLA), a broad-spectrum macrolide, is a poorly soluble drug with dissolution rate limited absorption. The aim of this investigation was to prepare CLA nanoparticles from a ternary ground mixture in the presence of sodium lauryl sulfate (SLS) and polyvinyl pyrrolidone (PVP) as co-grinding water-soluble compounds, in order to improve the drug dissolution rate. Different weight rati...

In this paper we propose a new incremental spike sorting model that automatically eliminates refractory period violations, accounts for action potential waveform drift, and can handle “appearance” and “disappearance” of neurons. Our approach is to augment a known time-varying Dirichlet process that ties together a sequence of infinite Gaussian mixture models, one per action potential waveform o...

One of the common problems with clustering is that the generated clusters often do not match user expectations. This paper proposes a novel probabilistic framework that exploits supervised information in a discriminative and transferable manner to generate better clustering of unlabeled data. The supervision is provided by revealing the cluster assignments for some subset of the ground truth cl...

Changes in molecular states of p-dimethylaminobenzonitrile (DMABN) coground with β-cyclodextrin (β-CD) were examined using solid-state fluorescence measurements. Formation of a DMABN/β-CD inclusion complex by coprecipitation was confirmed by powder X-ray diffraction measurement. The powder X-ray diffraction pattern of the ground mixture was a halo pattern and differed from the pattern of the mi...