background: in conventional radiation therapy, regarding normal tissue tolerance, the treatment of bulk tumors is one of the remaining challenges. grid radiation therapy (grt) is a technique to deliver high doses, approximately 15 – 20 gy per fraction, to several small volumes located in a large radiation field. this can be performed using a grid block. the current work has concentrated on the ...

background: an effective method for management of large and bulky malignant tumors. this treatment modality is also known as specially fractionated radiation therapy (sfrt). in this treatment technique a grid block converted the open radiation field into a series of pencil beams. dosimetric characteristics of an external beam grid radiation field have been investigated using experimental and mo...

Introduction: Radiation-induced bystander effect (RIBE) is a well-known response associated with the induction of radiation effects in non-irradiated cells via signaling of hit ones. As this so-called phenomenon has been largely investigated in low dose levels, few studies focused on higher dose levels such as grid therapy. Grid therapy or spatially fractionated gri...

Introduction: GRID therapy is a treatment modality in which a high dose of radiation in a single fraction is given to the tumor. This technique previously was used to treat bulky tumors with orthovoltage beams. Recently, studies have been conducted to suggest that GRID therapy with megavoltage photons can be useful in palliative treatments. On the other hand, there has always ...

Background: In conventional radiation therapy, regarding normal tissue tolerance, the treatment of bulk tumors is one of the remaining challenges. Grid Radiation Therapy (GRT) is a technique to deliver high doses, approximately 15 – 20 Gy per fraction, to several small volumes located in a large radiation field. This can be performed using a grid block. The current work has concentrate...

In the present study, a case was reported concerning a patient with a bulky extremity soft tissue sarcoma treated with spatially fractionated Grid therapy and then followed by standard external beam radiotherapy. Treatment was performed using a Grid block to deliver 15 Gy in one fraction. There was one week interval break before EBRT treatment with 50 Gy in 25 fractions for the neoadjuvant exte...

Background: An effective method for management of large and bulky malignant tumors. This treatment modality is also known as Specially Fractionated Radiation Therapy (SFRT). In this treatment technique a grid block converted the open radiation field into a series of pencil beams. Dosimetric characteristics of an external beam grid radiation field have been investigated using experimental and Mo...

Grid therapy is a treatment technique that has been introduced for patients with advanced bulky tumors. The purpose of this study is to investigate the effect of the radiation sensitivity of the tumors and the design of the grid blocks on the clinical response of grid therapy. The Monte Carlo simulation technique is used to determine the dose distribution through a grid block that was used for ...