Granuloma faciale is a chronic, benign, cutaneous vasculitis with well-established clinical and morphological patterns, but with an unknown etiology. This study describes clinical and pathologic aspects of patients diagnosed with granuloma faciale. The authors analyzed demographic, clinical, morphological and immunohistochemical data from patients with a final diagnosis of granuloma faciale, co...

Sir, Granuloma faciale (GF) is a rare, but distinct in ̄ammatory dermatosis of unknown origin diagnosed on a combination of clinical and histopathological ®ndings. The clinical presentation may be very variable and can simulate a great variety of dermatosis. The treatment is not well established and in many cases may be unsatisfying and frustrating. We report here a case of disabling and dis®gur...

We report the case of a 55-year-old Japanese patient with granuloma faciale (GF) successfully treated with topical tacrolimus and describe the immunohistochemical study. Immunohistochemical staining revealed that the patient's granuloma contained CD3(+), CD4(+), CD8(+), CD68(+) and CD163(+) cells. Interestingly, these cells contained granulysin(+) T cells and lacked Foxp3(high+) regulatory T ce...

Granuloma faciale is a rare dermatosis of chronic course, benign, usually asymptomatic, first described in 1945 by Wingley. It is characterized by the appearance of well-defined, single or multiple papules, plaques and nodules, predominantly located in sun-exposed areas, especially the face. In this work we report the case of a female patient, 58 years old, evolving for ten years with multiple ...

introduction: granuloma faciale is an uncommon inflammatory dermatosis which usually affects the face and is often resistant to treatment. case report: a 39-year-old english lady with fitzpatrick skin phototype ii presented with typical lesions of granuloma faciale, confirmed on biopsy, on her cheeks and nose. treatment with scleroplus pulsed dye laser (candela corporation, wayland, mass) produ...

Granuloma faciale (GF) is a rare benign chronic inflammatory dermatosis often difficult to distinguish clinically from other diseases, both and neoplastic. Dermoscopy can be helpful diagnostic tool indeed several dermoscopic criteria observed in GF have been described literature. We present two patients affected by which we rosettes.