effects of formulation parameters on the fractional release profile of diclofenac sodium from matrices having the manufacturing formulation ingredients are studied. as a content of cetyl alcohol (rate controlling agent) in the matrix increases, the fractional release decreases. the fractional release increases either by increasing sucrose content outside the granule or by decreasing sucrose con...

Effects of formulation parameters on the fractional release profile of diclofenac sodium from matrices having the manufacturing formulation ingredients are studied. As a content of cetyl alcohol (rate controlling agent) in the matrix increases, the fractional release decreases. The fractional release increases either by increasing sucrose content outside the granule or by decreasing sucrose...

Experimental work was carried out to investigate the influence of impeller speed, granulation time, binder mass and their interactions on granule size distribution, mean size and binder content distribution in a conical high shear granulator. It was observed that the response of high shear granulation to changes in process parameters varies significantly from one operating condition to anot...

experimental work was carried out to investigate the influence of impeller speed, granulation time, binder mass and their interactions on granule size distribution, mean size and binder content distribution in a conical high shear granulator. it was observed that the response of high shear granulation to changes in process parameters varies significantly from one operating condition to another....

the dentate gyrus of hippocampus has long been considered as a focal point for studies on mechanisms responsible for the development of temporal lobe epilepsy (tle). change in intrinsic properties of dentate gyrus granule cells (gcs) has been considered as an important factor responsible in temporal lobe seizures. in this study, we evaluated the intrinsic properties of gcs, during acute phase o...

up flow anaerobic sludge blanket (uasb) reactors have been increasingly used for industrial wastewater treatment. because of existing problems in startup step of these reactors, in this research the startup of a uasb in pilot scale and room temperature condition was studied. the total height of uasb reactor was 270 cm and effective height was 240 cm. diameter of the reactor in lower part was 20...

in spite of the existing reports on behavioural and biochemical changes related to the cerebellum due to noise stress, not much is known about the effect of noise stress on the neuronal changes in the cerebellum. the present study aims at investigating the effects from one week noise exposure on granule cell number and purkinje cell volume within the neonate rat cerebellum. 15-day-old male wist...

background: indoor residual spraying (irs) is functioned as national interventions against malaria in southeastern foci of iran and deltamethrin wp one of the insecticides have been used since past decade. in this study, the residual activity of the wettable granule (wg) was studied on different surfaces in hut scale trial against anopheles stephensi   in iranshahr district, southeastern iran. ...

Understanding the relationship between processing parameters of fluidized bed wet granulation and the characteristics of intermediate and final products is crucial in the pharmaceutical processes. This research examined a fluidized bed wet granulation process containing a cornstarch solution as binder and lactose particles as powder. The design of experiment (DoE) was performed according to an ...

The geometric dimensions of the copper shell formed by chemical deposition on a spherical polyethylene granule were calculated. It is shown that main factor determining thickness layer initial size granule. processes destruction during thermal expansion polymer are considered. values limit temperatures in which still retains its integrity depending