نتایج جستجو برای: graf

تعداد نتایج: 1084  

بوستانی, حسن, رستمی, اسماعیل, صادقیان, محمد هادی, قوطاسلو, عباس, کیانی قلعه سردی, امید,

Background and Objective: Acute lymphoblastic leukemia is a disorder caused by the proliferation of malignant immature lymphoid cells. GRAF (GTPase regulator associated with focal adhesion kinase) which acts as a tumor suppressor gene is disabled in hematologic malignancies due to genetic and epigenetic abnormalities. In this study, GRAF gene expression was inspected in patients with B-ALL. ...

Introduction: GTPase regulator associated with focal adhesion kinase (GRAF) is a recently identified GTPase activating protein that has the tumor suppressor properties. However, the expression level of GRAF in leukemia had received less attention. The main purpose of this research was the evaluating of the expression level of GRAF in patients with acute myeloid leukemia (AML). Materials and met...

Journal: :journal of basic research in medical sciences 0
mohammad hadi sadeghian department of hematology,faculty of paramedical sciences, ilam university of medical sciences, ilam, iran mohammad alidadi 4. department of physiology, faculty of medicine, ilam university of medical sciences, ilam, iran hossein ayatollahi 1. department of hematology and blood bank, cancer molecular pathology research center, faculty of medicine, mashhad university of medical sciences, mashhad, iran mohammad reza keramati 2. department of hematology, ghaem hospital, mashhad university of medical sciences, mashhad, iran enaiat anvari 1. department of hematology and blood bank, cancer molecular pathology research center, faculty of medicine, mashhad university of medical sciences, mashhad, iran hasan boustani 3. neonatal research center, imam reza hospital, faculty of medicine, mashhad university of medical sciences, mashhad, iran

introduction: gtpase regulator associated with focal adhesion kinase (graf) is a recently identified gtpase activating protein that has the tumor suppressor properties. however, the expression level of graf in leukemia had received less attention. the main purpose of this research was the evaluating of the expression level of graf in patients with acute myeloid leukemia (aml). materials and met...

Journal: :Journal of cell science 1999
J M Taylor M M Macklem J T Parsons

Graf, the GTPase regulator associated with focal adhesion kinase was previously shown to have GAP activity for &Rgr; A and Cdc42 in vitro (Hildebrand et al 1996 Mol. Cell Biol. 16: 3169-3178). In this study we sought to determine whether Graf acted at the level of Cdc42, Rho, or both in vivo and whether Graf was a signal terminator or transducer for these proteins. Microinjection of Graf cDNA i...

2010
Zhen Qian Jun Qian Jiang Lin Dong-ming Yao Qin Chen Run-bi Ji Yun Li Gao-fei Xiao Jian-yong Li

BACKGROUND GTPase regulator associated with the focal adhesion kinase (GRAF), a putative tumor suppressor gene, is found inactivated in hematopoietic malignancies by either genetic or epigenetic abnormalities. However, the expression level of GRAF gene has not yet been studied in leukemia. The aim of this study was to investigate the expression level of GRAF gene in those patients with myeloid ...

Journal: :Fraktal 2023

Graf koprima pada grup bilangan bulat modulo memiliki banyak aplikasi penting dalam matematika diskrit dan kriptografi. Indeks Harary dari graf sangat berguna ilmu komputer, terutama perhitungan properti aljabarik, topologi, struktur graf. Pada artikel ini didapatkan Hararay untuk yang berorde perpangkatan prima, yakni kuadrat jumlah anggota dikurangi satu.

Journal: :Bimaster : Buletin Ilmiah Matematika, Statistika dan Terapannya 2020

Journal: :FIBONACCI: Jurnal Pendidikan Matematika dan Matematika 2019

Journal: :Language Resources and Evaluation 2014
Nancy Ide Keith Suderman

This paper overviews the International Standards Organization Linguistic Annotation Framework (ISO LAF) developed in ISO TC37 SC4. We describe the XML serialization of ISO LAF, the Graph Annotation Format (GrAF) and discuss the rationale behind the various decisions that were made in determining the standard. We describe the structure of the GrAF headers in detail and provide multiple examples ...

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