نتایج جستجو برای: gonadectomized rat

تعداد نتایج: 275787  

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2002
Derek T Solum Robert J Handa

During development, estrogen has a variety of effects on morphological and electrophysiological properties of hippocampal neurons. Brain-derived neurotrophic factor (BDNF) also plays an important role in the survival and differentiation of neurons during development. We examined the effects of gonadectomy with and without estrogen replacement on the mRNA and protein of BDNF and its receptor, tr...

حیدریه, نسرین, خوش سخن, مریم, رمضانی متقاعد, مهرناز,

Introduction: Depression is one of the most common mental disorders, which its effective treatment maintains an acceptable level of performance in patients. Concerning the different effects of sexual glands on various physiological phenomena such as depression, the purpose of this study was investigation of the effect of Atorvastatin on depression by forced swimming stress model in gonadectomiz...

2010
Hirotaka MATsuMoTo Youichiro KATo Koichi SuzuKi aRd Akira KAwAoi

Employing diisopropanolnitrosamine (DIPN)-induced rat thyroid tumors as an experimental model, the possible role of androgen in thyroid carcinogenesis was examined. The rate of tumer induction was higher in male than female rats. In male rats, at 15 to 20 weeks after the final DIPN iajection, the thyroid glands were remarkably enlarged and were being replaced by carcinoma tissues. Castration of...

Journal: :The Biochemical journal 1969
R E Pinto W Bartley

1. Glutathione peroxidase activity in the livers of sham-operated female rats was about 60% higher than in similarly treated male rats. The value in the ovariectomized female was about the same as that in the castrated or sham-operated male. 2. Glutathione peroxidase activity changed during the oestrous cycle. The highest value was in oestrus, and was about 50% higher than the lowest activity, ...

Journal: :Circulation research 1984
T F Schaible A Malhotra G Ciambrone J Scheuer

To examine the influence of the sex hormones on mechanical properties and biochemistry of the adult heart, we studied left ventricular function and cardiac contractile proteins in hearts from 20-week-old male and female rats that had been gonadectomized at 18 days of age, compared with hearts from sham-operated animals. Testosterone and estradiol were not detectable in serum from male and femal...

2015
Mohadeseh Chahkandi Nayerreh Askari Gholamreza Asadikaram

BACKGROUND Opiates affect blood factors as well as pain and inflammation in a gender-dependent manner. The aim of the present study was to evaluate the effects of morphine on serum glucose, cholesterol, triglycerides, and urea in gonadectomized and inflammation conditions. METHODS Animals were divided as follows: control group, carrageenan and chronic morphine recipients, acute morphine recip...

Journal: :Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association 1997
M V Root S D Johnston P N Olson

Male (n = 6/group) and female (n = 6/group) kittens were gonadectomized at 7 weeks (prepuberally) or 7 months of age (postpuberally), or left intact. Lateral radiographic projections of the right forelimb were made from 4 months of age until the distal radial physis was closed, or 24 months of age. In males, distal radial physeal closure was delayed in both groups of gonadectomized animals, com...

Journal: :Hypertension 1997
J T Crofton L Share

We have shown previously that, in rats with deoxycorticosterone (DOC)-salt hypertension, arterial blood pressure rises more rapidly and reaches a higher level in male than in female rats and that the course of the hypertension was ameliorated by gonadectomy in male rats and exacerbated by gonadectomy in female rats. The present investigation was undertaken to examine the role of the gonadal ste...

Journal: :Hypertension 1992
Y F Chen A J Naftilan S Oparil

Our previous studies demonstrated that the sexually dimorphic pattern of hypertension in the spontaneously hypertensive rat is androgen dependent. Gonadectomy retards the development of hypertension in young males, but not in females, and administration of testosterone propionate to gonadectomized spontaneously hypertensive rats of both sexes confers a male pattern of blood pressure development...

Journal: Addiction and Health 2015
Gholamreza Asadikaram, Mohadeseh Chahkandi Nayerreh Askari

Background: Opiates affect blood factors as well as pain and inflammation in a gender-dependent manner. The aim of the present study was to evaluate the effects of morphine on serum glucose, cholesterol, triglycerides, and urea in gonadectomized and inflammation conditions. Methods: Animals were divided as follows: control group, carrageenan and chronic morphine recipients, acute morphine recip...

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