نتایج جستجو برای: gonad development

تعداد نتایج: 1417708  

Journal: :Mechanisms of Development 2000
Karin Wertz Bernhard G Herrmann

The vertebrate gonad develops from the intermediate mesoderm as an initially bipotential organ anlage, the genital ridge. In mammals, Sry acts as a genetic switch towards testis development. Sox9 has been shown to act downstream of Sry in testis development, while Dax1 appears to counteract Sry. Few more genes have been implicated in early gonad development. However, the genetic networks contro...

Journal: :The International journal of developmental biology 2010
Rafal P Piprek

The direction of gonadal development is established through the predominance of one of two sex-determining pathways in bipotential gonads. When Sry is expressed, the male pathway prevails and a series of prominent changes in morphology and function of the gonad lead to testis differentiation. In the absence of Sry, the female pathway gains control of gonadal development, resulting in a lack of ...

Journal: :Asian journal of andrology 2012
Kathryn McClelland Josephine Bowles Peter Koopman

Disorders of sex development often arise from anomalies in the molecular or cellular networks that guide the differentiation of the embryonic gonad into either a testis or an ovary, two functionally distinct organs. The activation of the Y-linked gene Sry (sex-determining region Y) and its downstream target Sox9 (Sry box-containing gene 9) triggers testis differentiation by stimulating the diff...

Journal: :Molecules 2018
Kunhuang Han Yanbin Dai Ziping Zhang Zhihua Zou Yilei Wang

Ubiquitin C-terminal hydrolases (UCHLs) are a subset of deubiquitinating enzymes, and are involved in numerous physiological processes. However, the role of UCHLs during gonad development has not been studied in crustaceans. In this study, we have first cloned and analyzed expression profiling of Sp-uchl3 and Sp-uchl5 genes from mud crab Scylla paramamosain. The full-length cDNA of Sp-uchl3 is ...

2017
Dena M Leerberg Kaori Sano Bruce W Draper

The vertebrate ovary and testis develop from a sexually indifferent gonad. During early development of the organism, primordial germ cells (the gamete lineage) and somatic gonad cells coalesce and begin to undergo growth and morphogenesis to form this bipotential gonad. Although this aspect of development is requisite for a fertile adult, little is known about the genetic regulation of early go...

Journal: :Brazilian journal of biology = Revista brasleira de biologia 2008
F G Araújo M A Silva M C C Azevedo J N S Santos

The pattern of the use of the Sepetiba Bay, a semi-closed 450 km(2) area in southeastern Brazil, by Anchoa tricolor was investigated to assess spawning period, recruitment and to detect spatial-temporal patterns of this major fishery resource. Fishes were sampled by seine nets, from spring, 1998 to winter, 1999 and by beach seine, from spring, 1998 to winter, 2000. Reproductive season, measured...

Journal: :Development 1995
M Boyle S DiNardo

The adult ovaries and testes contain several specialized somatic cell types that support the differentiation of germ cells into mature gametes. Each of these cell types arise from mesodermal cells that constitute the embryonic gonad. To explore the mechanisms governing the development and differentiation of these cells, we focus on the formation of the gonad during Drosophila development. Using...

Journal: :Current Biology 2001
Peter Koopman

The formation of testes or ovaries in the mammalian embryo is critical in determining sexual identity and the ability to reproduce. Recent studies have begun to illuminate the cellular signalling events required for development of functional testes.

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2008
Joaquín Rodríguez-León Concepción Rodríguez Esteban Mercè Martí Belén Santiago-Josefat Ilir Dubova Xavier Rubiralta Juan Carlos Izpisúa Belmonte

Organ shape and size, and, ultimately, organ function, relate in part to the cell and tissue spatial arrangement that takes place during embryonic development. Despite great advances in the genetic regulatory networks responsible for tissue and organ development, it is not yet clearly understood how specific gene functions are linked to the specific morphogenetic processes underlying the intern...

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