to confirm the side-effects of gold sodium thiomalate (gstm), we carried out a retrospective study examining 102 consecutive patients with rheumatoid arthritis attending the rheumatology unit of hafez hospital, shiraz, iran, in whom gstm was initiated between 1983-1989. only patients with classical or definite ra (ara criteria) we(e included in this study. patients were categorized as having de...

to determine the complications of gold sodium thiomalate therapy in rheumatoid arthritis (ra), 32 patients with active ra (27 female, 5 male) treated for a mean period of 28 ? 14 weeks were studied. from these patients, 62.5 (46-79) percent showed at least one drug reaction. pruritus was the most common complication occurred in 59 (42-76) percents, and was accompanied by skin rush in 37 (15-57)...

sodium bentonite can bind to dietary pigment and decreases yolk color scale. sodium bentonite is one of the main parts of formycine® gold, the effect of different levels of formycine® gold and dietary pigment on egg quality, egg yolk color and performance criteria of laying hens from 26 to 34 week of age were studied. one hundred ninety two hy-line hens were divided into 24 groups of 8 birds ea...

Sodium bentonite can bind to dietary pigment and decreases yolk color scale. Sodium bentonite is one of the main parts of Formycine® Gold, the effect of different levels of Formycine® Gold and dietary pigment on egg quality, egg yolk color and performance criteria of laying hens from 26 to 34 week of age were studied. One hundred ninety two Hy-Line hens were divided into 24 groups of 8 birds ea...

Endothelial adhesion molecules play an important role in the tissue recruitment of leukocytes in inflammatory conditions such as rheumatoid arthritis. We have investigated the effect of the antirheumatic drug gold sodium thiomalate on adhesion molecule protein and mRNA expression in cultured human endothelial cells. Gold sodium thiomalate inhibited cytokine (TNF, IL-1, IL-4)-stimulated expressi...

We have previously shown that cells with a high content of the gold-binding protein metallothionein (MT) are resistant to the growth inhibitory effects of gold(III) chloride and auranofin. To investigate whether MT confers resistance to sodium aurothiomalate two cell lines of cultured human epithelial (HE) cells were used; the parental cell line (HE) and a substrain (HE100) containing high leve...

Transformation of lymphocytes stimulated by mitogen, purified protein derivative, and in the mixed lymphocyte culture was significantly inhibited by gold sodium thiomate and gold sodium thiosulphate at concentrations of 5 X 10(-4) to 5 X 10(-5) mol/1.