abstract the gnrh analogue (agonist and antagonist gnrh) changed ovarian stimulation. on the one hand, it improved chances of pregnancy to obtain more oocytes and better embryos. this leads to an ovarian hyper-response, which can be complicated by the ovarian hyperstimulation syndrome (ohss). on the other hand, the gnrh analogue can prevent the incidence of ohss: gnrh antagonist protocols, gnrh...

gonadotropin releasing hormone (gnrh) plays a key role in reproduction. this decapeptide is synthesized and released by hypothalamus and induces the pituitary gonadotrop cells to release pituitary gonadotropin hormones. in some extrapituitary compartments gnrh and its receptor act as part of the autocrine regulatory system of cell proliferation. the anticancer activity of gnrh and its analogues...

The GnRH analogue (agonist and antagonist GnRH) changed ovarian stimulation. On the one hand, it improved chances of pregnancy to obtain more oocytes and better embryos. This leads to an ovarian hyper-response, which can be complicated by the ovarian hyperstimulation syndrome (OHSS). On the other hand, the GnRH analogue can prevent the incidence of OHSS: GnRH antagonist protocols, GnRH agonist ...

The GnRH analogue has been shown to be effective in the treatment of precocious puberty when given as a daily subcutaneous injection. We studied the effectiveness of a long-acting GnRH analogue, Triptoreline, for the treatment of central precocity, by suppressing gonadotropin and estradiol secretion in three children with true precocious puberty. One month after single dose intramuscular i...

the gnrh analogue has been shown to be effective in the treatment of precocious puberty when given as a daily subcutaneous injection. we studied the effectiveness of a long-acting gnrh analogue, triptoreline, for the treatment of central precocity, by suppressing gonadotropin and estradiol secretion in three children with true precocious puberty. one month after single dose intramuscular inject...

Gonadotropin releasing hormone (GnRH) plays a key role in reproduction. This decapeptide is synthesized and released by hypothalamus and induces the pituitary gonadotrop cells to release pituitary gonadotropin hormones. In some extrapituitary compartments GnRH and its receptor act as part of the autocrine regulatory system of cell proliferation. The anticancer activity of GnRH and its analogues...

LH release in response to pulsatile administration of small amounts of GnRH analogue in cows with follicular cysts was examined. The pulsatile administration of GnRH analogue induced a LH-surge like peak over 10 hr in both normal cows and cows with follicular cysts. The mean peak value of LH in follicular cystic cows did not differ significantly from that of normal cows. All the cows with cysts...

This study was designed to evaluate the reproductive performance of Japanese black cows following the 3rd injection of gonadotropin releasing hormone (GnRH) analogue administered concurrently with Ovsynch-based treatment on day 6 (day 1 = the day of ovulation). In Experiment 1, 12 cows were allocated into three groups: a control group that was subjected to Ovsynch treatment and then injected wi...

Methods We identified 72 girls diagnosed with central precocious puberty, and they were treated with GnRH analogue (GnRHa) to suppress pubertal progression from 1 January 2011 to 31 January 2012. GnRH stimulation tests were done before and 4 weeks after the third dose of the GnRH analogue. Information on clinical manifestations and laboratory data were obtained by reviewing medical records. All...

In rat anterior pituitary cell cultures GnRH (1nM) stimulated a pro-e increase in LH release into the medium from 1 to 8 h of incubation, while cellular LH showed a corresponding decrease. GnRH (1nM) neither modified the uptake nor the incorporation of [3H]-glucosamine and [3H]-proline into total protein. The incorporation of ["HI-proline into cellular LH also was unaffected by GnRH. In contras...