objectives: diabetes mellitus (dm) is the most common endocrine disease in children. massage therapy can improve glucose metabolism in dm. this study was conducted to determine the effect of swedish massage on the glycohemoglobin (hba1c) in children with dm. methods: this study was an semi-experimental (clinical trial) conducted on thirty-six children, 6-12 years old with (dm), recruited from a...

INTRODUCTION Glycohemoglobin (HbA1c) most accurately reflects the previous two to three months of glycaemic control. HbA1c should be measured regularly in all patients with diabetes, and values should be maintained below 7% to prevent the risk of chronic complications. Apart from the genetic variants of haemoglobins many other conditions also known to affect HbA1c measurements. In this study we...

The determination of glycohemoglobin [HbA1c, HbA1, or total glycohemoglobin (GHb)] has become an established procedure in the management of diabetes mellitus. Here, we describe the development of a simple, fluorescence, non-separation assay for the percentage of GHb (%GHb). The fluorescence of an eosin-boronic acid derivative when it was mixed with hemolysates of unwashed erythrocytes was quenc...

Measurement of glycohemoglobin has been recommended for the long-term assessment of glycemic control in diabetic patients. Because different analytical methods measure different glycohemoglobin species, it has been difficult to compare results between laboratories. Here we report 3 years of experience with calibration of an affinity chromatography method for measuring total glycohemoglobin (GHb...

Objectives: Diabetes mellitus (DM) is the most common endocrine disease in children. Massage therapy can improve glucose metabolism in DM. This study was conducted to determine the effect of Swedish massage on the Glycohemoglobin (HbA1c) in children with DM. Methods: This study was an semi-experimental (clinical trial) conducted on thirty-six children, 6-12 years old with (DM), recruited fro...

We describe a novel assay for measuring glycohemoglobin directly from anticoagulated whole blood with the Abbott IMx analyzer. The glycohemoglobin is labeled with a soluble polyanionic affinity reagent and the anionic complex is then captured with a cationic solid-phase matrix. Glycohemoglobin is quantified by measuring the quenching by heme of the static fluorescence from an added fluorophore....

Background: Diabetes mellitus is increasing day by throughout the globe. So, early diagnosis of diabetes crucially important in reduction complications. This study was conducted to determine correlation between glucose monitoring fasting blood and two hours postprandial with glycated hemoglobin (HbA1c) diabetic patients evaluate whether glycohemoglobin levels increase age both sexes Methods: A ...

BACKGROUND Previous work suggests that Japanese patients with type 2 diabetes mellitus (T2DM) may respond more favorably to a DPP-4 (dipeptidyl peptidase-4) inhibitor than Caucasians. We aimed to compare the efficacy of the DPP-4 inhibitor vildagliptin (50 mg twice daily [bid]) between Japanese and Caucasian populations. METHODS This analysis pooled data from 19 studies of drug-naïve patients...

Aim: It has been known for a long time that the presence of clinically silent hemoglobin (Hb) variants in blood samples could influence the measurement of glycohemoglobin (HbA1c) since these abnormal hemoglobins might interfere with some methodologies. In the present study we describe the first case of Hb Beckman in Turkey. Material and Methods: The variant was detected during the HbA1c measure...