objective: today, special attention is paid to the use of zirconium dioxide nanoparticle (nano-zro2), a neutral bioceramic metal, particularly for drug and gene delivery in medicine. however, there are some reports implying that use of nano-zro2 is associated with cytotoxic effects like inhibiting the cell proliferation, dna damage and apoptosis. in the present study, we examined whether nano-z...

BACKGROUND AND OBJECTIVES In this study, we aimed to investigate the effects of sevoflurane, desflurane and propofol maintenances on serum levels of selenium, copper, zinc, iron, malondialdehyde, and glutathion peroxidase measurements, and antioxidant capacity. METHODS 60 patients scheduled for unilateral lower extremity surgery which would be performed with tourniquet under general anesthesi...

Purified and microsomal preparations of prostaglandin H synthase catalyzed the arachidonic acid-dependent polymerization of acetaminophen and, in the presence of GSH, catalyzed the formation of 3-(glutathion-S-yl)acetaminophen. The formation of these products was inhibited by indomethacin and by purging reaction mixtures with argon. When H2O2 replaced arachidonic acid, neither indomethacin nor ...

The response of transgenic Nicotiana tabacum L. plants carrying the gene for potyviral non-structural P3 protein to Potato virus Y (strain NTN) infection was not significantly different from the wild type. The activities of antioxidant enzymes catalase (CAT), glutathion reductase (GR), ascorbate peroxidase (APOD) and superoxid dismutase (SOD), determined in systemically infected leaves at early...

The antioxidant defense system of the medicinal plant Raphanus sativus L. tuber root in terms certain enzymes (ascorbat peroxidase, glutathion reductase, catalase, superoxide dismutase) and lipid peroxidation against gray mold disease caused by Botrytis cinerea fungus on Vicia faba (bean) leaves was analyzed spectrophotometrically. V. plants were grown from seed under controlled conditions. A s...

Exercise-induced muscle oxidative stress may be involved in the myopathy associated with chronic obstructive pulmonary disease (COPD). This study was designed to look at whether local exercise induces muscle oxidative stress and whether this oxidative stress may be associated with the reduced muscle endurance in patients with COPD. Quadriceps endurance was measured in 12 patients with COPD (FEV...

abstract        background and objective: peroxidases catalyze protein oxidation and lipid peroxidation. the activity of these enzymes in nerve cells is involved in causing disorders such as alzheimer's and parkinson's disease. this study investigated the effect of citrus aurantium, foeniculum vulgare and rosmarinus officinalis essential oils on activity of peroxidase enzyme.       me...