objective: the purpose of the present study was to examine the impact of menstrual cycle abnormalities among patients with polycystic ovary syndrome (pcos) on biochemical and anthropometric characteristics. materials and methods: we conducted a prospective observational study of patients 17-35 years of age with pcos that attended the department of gynecological endocrinology of our hospital. re...

abstract background: gestational diabetes is the second common disorder in pregnancy period, which is detected in 24-28 weeks of gestational age through screening tests in low-risk women. the women with gestational diabetes are prone to prenatal mortality and development of future diabetes. therefore, detection of these individuals in the fi rst trimester and conducting preventive interventions...

background: the risk of gestational diabetes mellitus (gdm) in accordance to body mass index (bmi) is often based on studies where the calculation of bmi is frequently self-reported and is usually unreliable. we evaluated the risk of an abnormal oral glucose tolerance test (ogtt) in a population where bmi was measured and selective screening for gdm was practiced. methods: we carried out a pros...

Impaired glucose tolerance has several adverse effects on growing fetus. In this study we evaluated the effect of excessive weight gain during pregnancy on the risk of glucose intolerance in pregnant women. A case-control study was conducted through which the glucose tolerance status after 100 gram oral glucose intake was compared between 60 pregnant women with maximum 10 weeks of gestation and...

Glucose intolerance frequently is found in hepatocellular carcinoma (HCC) patients with hepatitis C virus (HCV) infection; however, the significance of glucose intolerance remains unclear. In addition, SH2 domain-containing inositol phosphatase (SHIP) 2 is a negative regulator of intracellular insulin signaling; however, changes in SHIP2 expression have not been investigated in HCC. To assess t...