background: to estimate the prevalence of small intestine bacterial overgrowth (sibo) among patients with irritable bowel syndrome (ibs) versus healthy subjects with the use of a glucose breath test (gbt) in our geographical area. materials and methods: this study included a total of 80 consecutive patients; 40 with ibs based on rome iii criteria and 40 healthy controls with similar age and sex...

background: small intestinal bacterial overgrowth (sibo) may have a role in the pathophysiology of irritable bowel syndrome (ibs). so, the aim of this study was to assess the association between sibo and ibs by using glucose breath test (gbt) in kerman city as the first study in iranian population. method: 107 patients with ibs and 107 healthy individualswere enrolled in our study. all the part...

Aim The aim was to investigate breath test outcomes in patients with suspected SIBO and indicative symptoms of SIBO, diagnosed by breath testing. Background Breath testing is used to detect small intestinal bacterial overgrowth (SIBO) by measuring hydrogen and methane produced by intestinal bacteria. Methods This retrospective cross sectional study included 311 patients with gastrointestina...

Background: The prevalence of genetically determined lactase non-persistence is based on the results of the lactose H 2 breath test. This test, however, is an indirect test, which might lead to misinterpretation. Design: We determined lactase activity in healthy Chinese and Dutch students using a novel C-lactose digestion test. The cut-off value of this test was established in a Chinese populat...

Hydrogen breath tests using various substrates like glucose, lactulose, lactose and fructose are being used more and more to diagnose small intestinal bacterial overgrowth (SIBO) and lactose or fructose malabsorption. Though quantitative culture of jejunal aspirate is considered as gold standard for the diagnosis of SIBO, hydrogen breath tests, in spite of their low sensitivity, are popular for...

OBJECTIVE With increasing emphasis on the recognition of the metabolic syndrome and early type 2 diabetes, a clinically useful measure of insulin resistance is desirable. The purpose of this study was to evaluate whether an index of glucose metabolism, as measured by (13)CO(2) generation from ingested [(13)C]glucose, would correlate with indexes from the hyperinsulinemic-euglycemic clamp. RES...

The frequency of negative hydrogen breath tests due to colonic bacterial flora which are unable to produce hydrogen was determined after oral lactulose challenge in 98 healthy Dutch schoolchildren. There was a negative result in 9.2%. The probability of a false normal lactose breath test (1:77) was calculated from these results together with those from a separate group of children with lactose ...

Objective. To evaluate the efficacy of the [(13)C]glucose breath test for measuring insulin resistance in Mexican adults with different glycemic states. Research Design and Methods. Fifty-eight adults underwent a [(13)C]glucose breath test with simultaneous measurement of total CO(2) production by indirect calorimetry, at baseline and 90 minutes after the ingestion of 15 g of dextrose and 25 mg...

BACKGROUND Many volatile organic compounds are present in exhaled breath and may represent by-products of endogenous biological processes. Ethanol is produced via alcoholic fermentation of glucose by gut bacteria and yeast, while acetone derives from oxidations of free fatty acids, influenced by glucose metabolism. We hypothesized that the integrated analysis of breath ethanol and acetone would...

OBJECTIVE To evaluate the incidence of small bowel bacterial overgrowth (SBBO) in children treated with omeprazole, and to test whether probiotics influence the incidence. METHODS A double-blinded, placebo-controlled trial was performed in 70 children treated orally during four weeks with 20mg omeprazole per day. Lactobacillus rhamnosus R0011 (1.9×10(9) cfu) and Lactobacillus acidophilus R005...