recent studies have shown that glucocorticoids may have modulatory effect on anxiety reactions. this effect may occur with opioid system interference. according to that, the purpose of this research is to assess the effect of dexamethasone as glucocorticoid agonist and its interaction with opioidergic system on the anxiety modulatory effect in plus maze model in mice. male white mice with mediu...

ba ckground: liver cancer is one of the deadly cancers with high prevalence in the east asia. likewise most of diseases, herbs and herbal medicine could be an easy and cost effective tool in prevention and possible cancer treatment. the present study investigated the ability of orthosiphon stamineus benth decoction to protect liver against hepatocellular carcinoma in carcinogenesis-induced anim...

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Some studies suggested that glucocorticoid receptors activities can modulate fear and anxiety. According to that, the purpose of this research is to assess the modulatory effect of glucocorticoid receptors on the anxiety assessed in plus maze. In this research mice with medium weight of 20-25 g were used. The male and female animals separately sorted in two groups as control and experiment rand...

some studies suggested that glucocorticoid receptors activities can modulate fear and anxiety. according to that, the purpose of this research is to assess the modulatory effect of glucocorticoid receptors on the anxiety assessed in plus maze. in this research mice with medium weight of 20-25 g were used. the male and female animals separately sorted in two groups as control and experiment rand...

objective: strong evidence indicate that activity of glucocorticoid receptors is necessary for emotional memory processess and these effects probably are mediated by hipppocampal opioid receptors. the aim of this study was to test whether there were any interaction between glucocorticoid and hippocampal opiate receptors on consolidtaion and retrieval of spatial memory. materials and methods: in...

Introduction: Previous studies have indicated that stress levels of glucocorticoid hormones induce impairment of long term memory retrieval, but the underlying mechanisms (genomic or non-genomic) are not clear. To clarify this issue, we investigated the involvement of brain corticosteroid receptors and protein synthesis in the glucocorticoid-induced impairment of memory retrieval. Methods: 140 ...