glomerular development of the kidney was studied in newborn rats by electron microscopy. four different stages of glomerular development were defined: vesicle fonnation, s-shaped body stage, capillary loop fonnation, and glomerular maturation. in the fust stage, the mesenchymal cells form a spheroid mass. this is followed by the s-shaped body stage in which clefts appear in the mass. afterwards...

Glomerular development of the kidney was studied in newborn rats by electron microscopy. Four different stages of glomerular development were defined: vesicle fonnation, S-shaped body stage, capillary loop fonnation, and glomerular maturation. In the fust stage, the mesenchymal cells form a spheroid mass. This is followed by the S-shaped body stage in which clefts appear in the mass. Afte...

OBJECTIVE The capillary changes at the initial stage of diabetes may show an angioarchitecture clearly different from those of later stages and/or very severe glomerular change. However, the onset of alterations in the early phases is unclear. This study attempts to determine the structural alterations of the glomerular wall and vessels in the early stage of diabetes. MATERIAL AND METHODS Twe...

PURPOSE The study aims to assess the influence of the stage of chronic kidney disease and glomerular filtration rate on prevalence and degree of erectile dysfunction. MATERIALS AND METHODS This transversal study, conducted from May 2013 to December 2015, included patients with chronic kidney disease in conservative treatment, stages III/IV/V. Erectile dysfunction was evaluated by the Internat...

BACKGROUND/AIMS Studies have shown that kidney injury molecule-1 (KIM-1) is upregulated in damaged renal proximal tubules. In this study, we examined KIM-1 expression in glomerular epithelial cells in diabetic glomerulopathy. METHODS Renal histology, immunostaining and Western blot for protein level, and real-time PCR for mRNA expression of KIM-1 and podocyte markers were evaluated in untreat...

Marked hyperlipemia, involving all lipid fractions, is a regularly noted observation in the nephrotic syndrome (1). In contradistinction, the serum lipid concentration is believed to be almost unaffected in early stages of acute glomerular nephritis, even though one can find data in the literature that indicate that increased concentrations of serum cholesterol may rarely be noted (1-5). As a c...

Renal biopsy material from seven cases of the nephrotic syndrome due to focal glomerular sclerosis has been studied by light, electron, and immunofluorescent microscopy. The nature of glomerular basement membrane changes and the scar tissue was also studied. It was found that the glomerular basement membrane and mesangial matrix formed the major components of scar tissue. On the basis of a shor...

This review discusses various screening approaches for chronic kidney disease that are used in Europe. The criterion for defining chronic kidney disease in the various programs differs but is frequently limited to estimated glomerular filtration rate, thus offering only data on chronic kidney disease stages 3 and higher; however, screening should not be limited to measuring only estimated glome...