BACKGROUND Psycho-education is now considered as part of the integrated treatment for bipolar disorder. This study aimed to determine the efficacy of group psycho-education on medication adherence and global functioning of patients with bipolar disorder type I. METHODS 45 patients with bipolar disorder type I were allocated one of the three groups of psycho-education plus pharmacotherapy, pha...

BACKGROUND To evaluate effectiveness outcomes in a real-world setting in patients with schizophrenia initiating risperidone long-acting therapy (RLAT). METHODS This was a 24-month, multicenter, prospective, longitudinal, observational study in patients with schizophrenia who were initiated on RLAT. Physicians could change treatment during the study as clinically warranted. Data were collected...

BACKGROUND A standardized definition of remission criteria in schizophrenia was proposed by the International group of NC Andreasen in 2005 (low symptom threshold for the eight core Positive and Negative Syndrome Scale (PANSS) symptoms for at least 6 consecutive months). METHODS A cross-sectional study of remission rate, using a 6-month follow-up to assess symptomatic stability, was conducted...

background: although evidences emphasize on the importance of aftercare programs to achieve continuity of care, different studies have revealed controversial results about the outcome. the objective of this study was to investigate the effect of aftercare program on outcome measures of patients with severe mental disorders. materials and methods: of a total 123 eligible patients with severe men...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background : schizophrenia requires a large share of medical resources due to its early onset and chronic and severe nature. compliance therapy is a therapy specifically designed to improve concordance with treatment for those with major mental illnesses. the aim of present study was to determine whether compliance therapy...

Objective: Axis V, which uses the Global Assessment of Functioning Scale in the multiaxial system ofDSM-III-R, is under review for DSM-IV. This article examines what is known about axis V and selectively reviews the literature on measures ofsocial functioning to identify potential alternatives to the Global Assessment of Functioning Scale. Method: About 25 studies on the use, reliability, and v...

BACKGROUND Many patients with schizophrenia and bipolar disorder have impaired insight and low medication adherence. The aim of this post hoc analysis was to explore the relationship between insight and medication adherence. METHODS We included 903 patients with schizophrenia or bipolar disorder who participated in an observational study conducted in Europe on the outcomes of patients treated...

BACKGROUND The relationship between social functioning and QOL in psychiatric patients has not been explicitly investigated before. AIMS To investigate the relationship between social functioning and QOL in a population of psychiatric outpatients (N = 410) with a broad spectrum of psychiatric disorders. METHOD Social functioning was assessed with the Groningen Social Behavior Questionnaire-...

Sex is a powerful modulator of disease susceptibility, course and outcome. The gene CACNA1C is among the best replicated vulnerability genes of bipolar disorder and schizophrenia. The aim of the present study was to investigate whether sex and a variant in CACNA1C (rs10774035 as a proxy for the well-acknowledged risk variant rs1006737) influence psychosocial adaptation in a large German patient...