نتایج جستجو برای: glipizide

تعداد نتایج: 326  

Journal: :Diabetes care 2002
Mary F Carroll Ahmad Izard Katrina Riboni Mark R Burge David S Schade

OBJECTIVE This study was designed to compare the efficacy of acute premeal administration of glipizide versus nateglinide in controlling postprandial hyperglycemia in subjects with non-insulin-requiring type 2 diabetes. RESEARCH DESIGN AND METHODS A total of 20 subjects (10 female, 10 male) with non-insulin-requiring type 2 diabetes were admitted overnight to the General Clinical Research Cen...

2013
Xin Chen Li-Li Xing Yu-Hai Tang Guang-Bin Zhang

A rapid and sensitive flow-injection chemiluminescence (CL) method for the determination of glipizide was developed on the basis of finding that glipizide can enhance the CL intensity of the luminol-K3Fe(CN)6 system. In optimum condition, the increased CL intensity was directly proportional to the concentration of glipizide in the range from 4.0×10-8 g/mL to 1.0×10-6 g/mL and the detection limi...

2017

Metformin helps your body to better use the insulin your pancreas. . Many people find the Extended Release version is more tolerable. Pharmacokinetics and pharmacodynamics of extended-release glipizide GITS compared with immediate-release glipizide in patients with type II diabetes . 2 Answers (question resolved) Posted in: glipizide xl, glipizide, pharmacy, generic Answer: ER or XL means exten...

2014
Cuiling Qi Qin Zhou Bin Li Yang Yang Liu Cao Yuxiang Ye Jiangchao Li Yi Ding Huiping Wang Jintao Wang Xiaodong He Qianqian Zhang Tian Lan Lee Kenneth Ka Ho Weidong Li Xiaoyu Song Jia Zhou Xuesong Yang Lijing Wang

Angiogenesis is involved in the development, progression and metastasis of various human cancers. Herein, we report the discovery of glipizide, a widely used drug for type 2 diabetes mellitus, as a promising anticancer agent through the inhibition of tumor angiogenesis. By high-throughput screening (HTS) of an FDA approved drug library utilizing our in vivo chick embryo chorioallantoic membrane...

Journal: :Journal of managed care pharmacy : JMCP 2011
Rachel A Skoff Nancee V Waterbury Robert F Shaw Jason A Egge Matthew Cantrell

BACKGROUND In 2009, the Veterans Health Administration (VHA) released a national bulletin regarding the risk of hypoglycemia associated with the use of glyburide in elderly patients with renal dysfunction. Providers were encouraged to avoid glyburide and use glipizide in patients with a calculated creatinine clearance (CrCl) of less than 50 mL per minute. Since this initiative, many veterans we...

2017
Uddin MD. Nazim Ji-Hong Moon You-Jin Lee Jae-Won Seol Yong Ju Kim Sang-Youel Park

The combination of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) with subsidiary agents is a promising anticancer strategy to conquer TRAIL resistance in malignant cells. Glipizide is a second-generation oral hypoglycemic medicine for the cure of type II diabetes because of its capability to selectively stimulate insulin secretion from β-cells. In this study, we revealed that ...

Journal: :Diabetes care 2005
Denice S Feig Gerald G Briggs Jennifer M Kraemer Peter J Ambrose David N Moskovitz Michael Nageotte Diane J Donat Guadalupe Padilla Stephanie Wan Julia Klein Gideon Koren

OBJECTIVE To determine if glyburide and glipizide are excreted into breast milk and if breast-feeding from women taking these drugs causes infant hypoglycemia. RESEARCH DESIGN AND METHODS We studied eight women who had received a single oral dose of 5 or 10 mg glyburide. Drug concentrations were measured in maternal blood and milk for 8 h after the dose. In a separate study, five women were g...

Journal: :The Journal of clinical investigation 1981
W S Putnam D K Andersen R S Jones H E Lebovitz

Investigative data have suggested that the extrapancreatic actions of the sulfonylureas may be paramount in their chronic antidiabetic action. The present study examines the effects of chronic sulfonylurea treatment on in vivo insulin action. Peripheral insulin levels, hepatic glucose production (Ra), and overall glucose disposal (Rd) were studied in six awake, normal dogs given both 0.5 and 1....

Journal: :research in pharmaceutical sciences 0

the purpose of the present study was to develop glipizide controlled release nanoparticles using alginate and chitosan thorough ionotropic controlled gelation method. glipizide is a frequently prescribed second generation sulfonylurea which lowers the blood glucose in type-two diabetics. quick absorption of the drug from the gastrointestinal tract along with short half- life of elimination make...

Journal: :Applied sciences 2022

Background: Oxidative stress, lipid profile and renal functions are well-known conventional risk factors for diabetes mellitus (DM). Metformin gliclazide popularly used monotherapy drugs the treatment of DM. Aims: This study aims to assess short-term single dual therapy glipizide/metformin on oxidative glycemic control, serum profiles function in diabetic rats. Methods: DM was induced rats with...

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