Department of Pharmacy, Kochi Medical School Hospital, 185-1 Kohasu, Oko, Nankoku, Kochi 783-8505, Japan Department of Biomedical Science, Kochi Medical Graduate School, 185-1 Kohasu, Oko, Nankoku, Kochi 783-8505, Japan Kochi Prefectural Industrial Technology Center, 3992-3 Nunoshida, Kochi, Kochi 781-5101, Japan Faculty of Agriculture, Kochi University, 200 Monobe, Nankoku, Kochi 783-8502, Jap...

Ethanol extract of ginger, turmeric and cinnamon was assessed for its antioxidant, antimicrobial and antiinflammatory activity. The antioxidant activity was determined by measuring FRAP (ferric reducing-antioxidant power) assay. The antibacterial efficacy was determined using paper disc method against different gram negative bacterial and sensitivity in terms of zones of inhibition of all extra...

BACKGROUND Macrophages play a dual role in host defence. They act as the first line of defence by mounting an inflammatory response to antigen exposure and also act as antigen presenting cells and initiate the adaptive immune response. They are also the primary infiltrating cells at the site of inflammation. Inhibition of macrophage activation is one of the possible approaches towards modulatin...

Bacterial biofilm formation can cause serious problems in clinical and industrial settings, which drives the development or screening of biofilm inhibitors. Some biofilm inhibitors have been screened from natural products or modified from natural compounds. Ginger has been used as a medicinal herb to treat infectious diseases for thousands of years, which leads to the hypothesis that it may con...

OBJECTIVE To evaluate the effect of ginger extract on the expression of NFkappaB and TNF-alpha in liver cancer-induced rats. METHODS Male Wistar rats were randomly divided into 5 groups based on diet: i) control (given normal rat chow), ii) olive oil, iii) ginger extract (100mg/kg body weight), iv) choline-deficient diet + 0.1% ethionine to induce liver cancer and v) choline-deficient diet + ...

BACKGROUND Diabetic cardiomyopathy is an important causal factor in morbidity and mortality among diabetic patients, and currently, no effective means are available to reverse its pathological progress. The purpose of the present study was to investigate the effect of ginger extract on apolipoproteins (apo) A and B, hyperhomocysteinemia, cathepsin G and leptin changes, as well as cardiac fibros...

background: in traditional medicine zingiber officinale used to regulate female menstural cycle and treat male infertility. recent studies have suggested the possible role of ginger extract in improving the testicular damage of busulfan. objective: the aim of this study was to evaluate the effects of zingiber officinale on the sperm parameters, testosterone level and the volume of the testes an...

The antibacterial activity of ethanol extract of Zingiber officinale Roscoe (ginger) and its combination with different salts like CuSO4, ZnSO4 and MnCl2 was investigated. Both Gram positive and Gram negative bacteria were tested by agar diffusion method. The results showed that ethanol extract of Zingiber officinale gave the maximum zone of inhibition at 50mg/ml concentrations against Escheric...

The aim of present work is to evaluate the antimicrobial activity of clove and ginger powder extracts on Streptococcus Mutans. An in-vitro study was conducted to assess effectiveness of 5%, 10%, and 50% clove and ginger powder extracts on Streptococcus mutans. The ditch plate method was used to test the antimicrobial activity. Ditches were prepared on blood agar plates with the help of punch ha...

Purpose. To evaluate antimicrobial effects of mixtures of Ethiopian honeys and ginger rhizome powder extracts on Staphylococcus aureus (ATCC 25923), Escherichia coli (ATCC 25922), Staphylococcus aureus (MRSA), Escherichia coli (R), and Klebsiella pneumoniae (R). Methods. Agar diffusion and broth assays were performed to determine susceptibility of these standard and resistant clinical bacteria ...